Peptide evidence.
Preparation by preparation.
A source-linked map of the Khavinson research tradition: defined sequences, parent tissue extracts, marketed products and the evidence that belongs to each.
Identity before inference
Finding a sequence in an extract does not make the extract interchangeable with that peptide. Product formulations need their own characterization.
Evidence in separate dimensions
Cell models, animal experiments and human reports remain separate. Human-derived cells are laboratory evidence. Patents, institute reports and journal articles retain their source type.
Visible gaps
This is a curated evidence map, not an exhaustive systematic review or an efficacy score. Source access, study design, preparation identity and independent replication require separate appraisal.
Corrections that matter.
- Vesugen: PMID 25051774 has a lower-limb title but an erectile-dysfunction abstract. It is retained as one conflicting record, not two patient cohorts.
- Ovagen: the accessible institute collection has 125 pages and a cohort description that conflicts with a later chat summary. The discrepancy remains explicit.
- Livagen: KEDA is retained; a conflicting KEDG label is not silently merged.
- Testagen: molecular identity remains unresolved in this collection.
Explore preparations and evidence.
Filters show which kinds of records are catalogued, not their quality. A paper may appear under several peptides; these entries are not independent study counts.
Showing 25 of 25 preparations.
Vilon ↗
Sequence / identity: KE
Related preparation: Thymalin. Composition paper identifies KE in the extract; detection does not establish equivalence.
Cell / tissue models
Animal models
- Investigation of antihypoxic properties of short peptides ↗
Journal publication · Synthetic peptide / defined-sequence research
Human reports
- Effect of vilon on the immunity status and coagulation hemostasis in patients of different age with diabetes mellitus ↗
Journal publication · Synthetic peptide / defined-sequence research
- Effect of thymomimetic vilon on blood coagulation system and fibrinolisis in diabetes mellitus type 1 patients of different age ↗
Journal publication · Synthetic peptide / defined-sequence research
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides: optimization of target therapeutic properties of the thymus medicine ↗
Analytical / composition study
Recovery targets
- Vilon: surgery, thermal trauma and macular-degeneration studies ↗
Lead · original evidence not verified
Pinealon ↗
Sequence / identity: EDR
Related preparation: Brain polypeptide complex; Cortexin is a distinct preparation. EDR detected in brain complex; not proof of equivalence to a clinical Cortexin product.
Cell / tissue models
- Biological activity of regulatory peptides in model experiments in vitro ↗
Journal publication · Synthetic peptide / defined-sequence research
Animal models
- Investigation of antihypoxic properties of short peptides ↗
Journal publication · Synthetic peptide / defined-sequence research
- Neuroprotective Effects of Tripeptides—Epigenetic Regulators in Mouse Model of Alzheimer’s Disease ↗
Animal / experimental
Human reports
- Analysis of some parameters of biological age and adaptation possibilities of workers of locomotive brigades ↗
Journal publication · Synthetic peptide / defined-sequence research
- The peptide correction of neurotic disorders among professional truck-drivers ↗
Human comparative study · Combination report
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides in the composition of polypeptide complexes isolated from animal organs ↗
Analytical / composition study
Recovery targets
- Pinealon + Crystagen: gymnast combination report ↗
Lead · original evidence not verified
- Laboratory-code dictionary acquisition ↗
Lead · original evidence not verified
Vesugen ↗
Sequence / identity: KED
Related preparation: Vessel complex / Vasolin. KED detected in vessel complex. The sequence and branded formulations are separate identity questions.
Cell / tissue models
Animal models
- Investigation of antihypoxic properties of short peptides ↗
Journal publication · Synthetic peptide / defined-sequence research
- Neuroprotective Effects of Tripeptides—Epigenetic Regulators in Mouse Model of Alzheimer’s Disease ↗
Animal / experimental
Human reports
- The efficacy of peptide bioregulators of vessels in lower limbs chronic arterial insufficiency treatment in old and elderly people ↗
Journal publication · Synthetic peptide / defined-sequence research
- The peptide correction of neurotic disorders among professional truck-drivers ↗
Human comparative study · Combination report
- Vesugen — originating-institute clinical report ↗
Institute report / commercial reproduction · Marketed product / formulation not independently verified
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides in the composition of polypeptide complexes isolated from animal organs ↗
Analytical / composition study
Recovery targets
- Vesugen: separate postoperative lower-limb cohort ↗
Lead · original evidence not verified
Pancragen ↗
Sequence / identity: KEDW; terminal form must be checked
Related preparation: Pancreatic polypeptide complex. KEDW reported in composition research; individual experiments may specify an amidated form.
Cell / tissue models
- Effects of pancragen on the differentiation of pancreatic cells during their ageing ↗
Journal publication · Synthetic peptide / defined-sequence research
- The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats ↗
Journal publication · Synthetic peptide / defined-sequence research
Animal models
- Impact of tetrapeptide pancragen on endocrine function of the pancreas in old monkeys ↗
Journal publication · Synthetic peptide / defined-sequence research
- Correction of impaired glucose tolerance using tetrapeptide (Pancragen) in old female rhesus monkeys ↗
Journal publication · Synthetic peptide / defined-sequence research
Human reports
- Prospects of using pancragen for correction of metabolic disorders in elderly people ↗
Journal publication · Synthetic peptide / defined-sequence research
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides in the composition of polypeptide complexes isolated from animal organs ↗
Analytical / composition study
Recovery targets
- Pancragen: additional institute cohort claim ↗
Lead · original evidence not verified
Epitalon ↗
Sequence / identity: AEDG
Related preparation: Epithalamin. AEDG detected in pineal complex after earlier sequence design.
Cell / tissue models
- Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro ↗
In vitro
- Biological activity of regulatory peptides in model experiments in vitro ↗
Journal publication · Synthetic peptide / defined-sequence research
Animal models
- Investigation of antihypoxic properties of short peptides ↗
Journal publication · Synthetic peptide / defined-sequence research
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Cartalax ↗
Sequence / identity: AED / T-31
Related preparation: Cartilage polypeptide complex (PCC). AED identified analytically; shared sequence does not establish preparation equivalence.
Cell / tissue models
Animal models
- OPTIMIZATION OF REPARATIVE OSTEOGENESIS JAWS ON AGING (PRECLINICAL STUDIES) ↗
Animal / experimental
Human reports
- AED bone/cartilage composition and reported knee-osteoarthritis comparison — RU2299741C1 ↗
Patent / reported experiments
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides in the composition of polypeptide complexes isolated from animal organs ↗
Analytical / composition study
Recovery targets
- PCC osteoarthritis Phase II program — original trial recovery target ↗
Trial not recovered · link is to the citing review
Livagen ↗
Sequence / identity: KEDA; conflicting KEDG label not adopted
Related preparation: Ventvil. Russian review distinguishes defined KEDA from liver extract.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Recovery targets
- Livagen hepatitis patent examples ↗
Lead · original evidence not verified
Cortagen ↗
Sequence / identity: AEDP — catalogue identity
Related preparation: Brain-peptide programme; direct product derivation unresolved. Shared tissue tradition, not verified identity with Cortexin.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Recovery targets
- Cortagen neurological patent examples ↗
Lead · original evidence not verified
Chonluten ↗
Sequence / identity: EDG
Related preparation: Bronchial mucosa complex. EDG reported in analytical work; product characterization is a separate question.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- Chonluten — originating-institute clinical report ↗
Institute report / commercial reproduction · Marketed product / formulation not independently verified
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides in the composition of polypeptide complexes isolated from animal organs ↗
Analytical / composition study
Recovery targets
- Peptides regulating inflammatory pathways in THP-1 cells ↗
Lead · original evidence not verified
Bronchogen ↗
Sequence / identity: AEDL
Related preparation: Bronchial mucosa complex. AEDL reported in the analytical paper; sequence order should be checked against each original experiment.
Cell / tissue models
- The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats ↗
Journal publication · Synthetic peptide / defined-sequence research
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides in the composition of polypeptide complexes isolated from animal organs ↗
Analytical / composition study
Cardiogen ↗
Sequence / identity: AEDR
Related preparation: Heart polypeptide complex, review-described. Analytical derivation reported in review; original characterization remains a gap.
Cell / tissue models
- The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats ↗
Journal publication · Synthetic peptide / defined-sequence research
Animal models
- Peptide substance restoring myocardium function — US7662789B2 ↗
Patent / reported experiments
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Prostamax ↗
Sequence / identity: KEDP — catalogue identity
Related preparation: Prostatilen is a distinct extract. Tissue association does not establish product equivalence.
Cell / tissue models
- The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats ↗
Journal publication · Synthetic peptide / defined-sequence research
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Thymogen ↗
Sequence / identity: EW
Related preparation: Thymalin. Composition literature discusses EW separately from KE and EDP.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Normophthal ↗
Sequence / identity: Identity retained at catalogue level
Related preparation: Retinalamin is a distinct extract. Shared retinal theme only; direct molecular derivation not established here.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Testagen ↗
Sequence / identity: Unresolved
Related preparation: Not established. No primary identity chain established in this collection.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Ovagen ↗
Sequence / identity: EDL association; formulation unverified
Related preparation: Do not assume equivalence to Ventvil. The renal culture paper studies T-35/EDL; linking it to a marketed Ovagen product requires characterization.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- Ovagen — originating-institute clinical report ↗
Institute report / commercial reproduction · Marketed product / formulation not independently verified
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Peptide Regulation of Cells Renewal Processes in Kidney Tissue Cultures from Young and Old Animals ↗
In vitro
Recovery targets
- Ovagen: conflicting clinical cohort claims ↗
Lead · original evidence not verified
- Laboratory-code dictionary acquisition ↗
Lead · original evidence not verified
Crystagen ↗
Sequence / identity: EDP association; formulation unverified
Related preparation: Thymic research tradition. Thymalin composition paper identifies EDP; marketed product equivalence is unverified.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- Crystagen — originating-institute clinical report ↗
Institute report / commercial reproduction · Marketed product / formulation not independently verified
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides: optimization of target therapeutic properties of the thymus medicine ↗
Analytical / composition study
Recovery targets
- Pinealon + Crystagen: gymnast combination report ↗
Lead · original evidence not verified
Epithalamin ↗
Sequence / identity: Mixture
Related preparation: Pineal tissue preparation. Contains multiple components; not interchangeable with AEDG.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- Geroprotective effect of epithalamine (pineal gland peptide preparation) in elderly subjects with accelerated aging ↗
Randomized trial · Tissue extract / extract combination
- Peptides of pineal gland and thymus prolong human life ↗
Human comparative study · Tissue extract / extract combination
- Effect of peptide preparation epithalamin on circadian rhythm of epiphyseal melatonin-producing function in elderly people ↗
Uncontrolled human report · Tissue extract / extract combination
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of Peptide AEDG in the Polypeptide Complex of the Pineal Gland ↗
Analytical / composition study
Thymalin ↗
Sequence / identity: Mixture
Related preparation: Thymic tissue preparation. Analytical identification of short sequences does not isolate their clinical contribution.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- The use of thymalin for the treatment of thermal injury ↗
Human comparative study · Tissue extract / extract combination
- Peptides of pineal gland and thymus prolong human life ↗
Human comparative study · Tissue extract / extract combination
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Identification of short peptides: optimization of target therapeutic properties of the thymus medicine ↗
Analytical / composition study
Cortexin ↗
Sequence / identity: Mixture
Related preparation: Brain-derived preparation. Clinical formulation distinct from Pinealon and Cortagen.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- Clinical efficacy and pharmacoeconomic characteristics of the neuroprotection with low doses of cortexin in the treatment of acute ischemic stroke ↗
Randomized trial · Tissue extract / extract combination
- An open clinical trial of cortexin in treatment of brain ischemia ↗
Uncontrolled human report · Tissue extract / extract combination
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Influence of cortexin on memory and attention ↗
Review · Tissue extract / extract combination
- Cerebrolysin for acute ischaemic stroke ↗
Review
PCC ↗
Sequence / identity: Mixture
Related preparation: Cartilage polypeptide complex. AED detection does not make the mixture Cartalax.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
- Peptide Regulation of Chondrogenic Stem Cell Differentiation ↗
Review
- Identification of short peptides in the composition of polypeptide complexes isolated from animal organs ↗
Analytical / composition study
Recovery targets
- PCC osteoarthritis Phase II program — original trial recovery target ↗
Trial not recovered · link is to the citing review
Prostatilen ↗
Sequence / identity: Mixture
Related preparation: Prostate-derived preparation. Separate from Prostamax.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- The use of prostatilen in treating patients with chronic prostatitis ↗
Uncontrolled human report · Tissue extract / extract combination
- The use of prostatilen in treating patients with prostatic diseases ↗
Uncontrolled human report · Tissue extract / extract combination
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Retinalamin ↗
Sequence / identity: Mixture
Related preparation: Retinal tissue preparation. No equivalence to Normophthal established.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
- Peptide bioregulators: delivery and efficacy ↗
Human comparative study · Tissue extract / extract combination
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Vasolin / Slavinorm ↗
Sequence / identity: Mixture
Related preparation: Vessel-derived complex. KED detection establishes a molecular link, not clinical equivalence.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.
Identity sources, reviews & unresolved leads
Context and identity
Ventvil ↗
Sequence / identity: Mixture
Related preparation: Liver-derived complex. Separate from Livagen/KEDA and Ovagen product claims.
Cell / tissue models
No direct record catalogued here. This is not evidence that no research exists.
Animal models
No direct record catalogued here. This is not evidence that no research exists.
Human reports
No direct record catalogued here. This is not evidence that no research exists.
Independent replication has not been established by this map. A review, follow-up or repeated citation is not an independent replication.