Slavinorm for intermittent claudication: randomized placebo-controlled trial
I. A. Suchkov, R. E. Kalinin, N. D. Mzhavanadze, A. A. Kamaev, A. G. Burenin, R. N. Larkov · 2023 · Angiology and Vascular Surgery. 29(1):23–33
Reported findings and study design
Seven-center, double-blind randomized four-arm comparison; 108 participants.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Pain-free walking distance | Active arms: +46.2% and +31.4%; placebo: +6.5%. | |
| At least 50% walking-distance improvement | 28% and 26% in active arms versus 3% with placebo; exact analysis denominators unavailable. | |
| Adverse-event comparison | p=0.59983; event counts absent. |
Recover the complete paper and clarify how the two placebo arms were analyzed. Short follow-up does not establish durable benefit or equivalent safety.
Source for the extracted data ↗ · Checked 2026-11-06
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- The abstract does not resolve analysis populations, placebo pooling, allocation concealment or missing data.
- No exact primary-outcome p value or confidence interval is supplied.
- A nonsignificant adverse-event comparison does not establish safety equivalence.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original society-hosted issue abstracts
Review depth: Complete original abstract checked; full article pending
Source access and review scope
Original journal abstract; four-arm design and selected outcomes checked.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Original clinical journal publication
Citation and original source
Original source: I. A. Suchkov, R. E. Kalinin, N. D. Mzhavanadze, A. A. Kamaev, A. G. Burenin, R. N. Larkov. Slavinorm for intermittent claudication: randomized placebo-controlled trial Angiology and Vascular Surgery. 29(1):23–33 2023.
Molekul research summary: https://molekul.io/research/slavinorm-arterial-rct-2023. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry