Kim’s five-peptide stress comparison: Chapter 6.4 evidence audit
A. E. Kim · 2024 · Kirov Military Medical Academy doctoral dissertation, 359 pp.; 2024 bibliography, related catalog entry dated 2025
Related evidence maps: Military & occupational ↗ · Missing author abstract
Reported findings and study design
The chapter identifies Cortexin, Pineamin, Prostatilen, Thymalin and Thymogen. The author highlights Pineamin in conclusions; original outcome tables and dose schedules have not been recovered.
Separate animal pharmacology experiments; participant-level and group-level counts for the five preparations unavailable
Protocol information
Peptide doses, routes, group assignments and timing require Chapter 6.4. The separate 25 mg/kg DMAE derivative was not Pineamin or another peptide.
Protocol source ↗ · Dissertation catalog, Chapter 6.4 heading, methods summary and conclusions; 49-page author abstract cataloged but not retrieved; original comparison tables unavailable
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Comparative preparations | Cortexin, Pineamin, Prostatilen, Thymalin and Thymogen | Chapter 6.4 title. Thymogen is a defined dipeptide; the five entries are not all tissue extracts. |
| Pineamin · animal stress models | Author highlights resistance to hypoxia, heat and cold | Selected conclusions only; dose, sample sizes, numerical results and ranking unavailable. |
| Five-agent effect estimates | Original comparative tables not recovered | No verified head-to-head result for Pineamin versus Cortexin, Thymalin, Thymogen or Prostatilen. |
| HIF-1α and TSPO | Predictive-marker hypothesis; peptide-specific causal data unavailable | Do not attribute nonpeptide DMAE-derivative findings to the peptide groups. |
| Document acquisition | 49-page dissertation abstract with tables cataloged in 2024 | Find the original author abstract and Chapter 6.4 before updating any ranking. |
This is a documented animal comparison with inaccessible efficacy tables. Existing Pineamin reproductive studies establish a separate clinical setting, not evidence for physical performance or environmental resilience.
Source for the extracted data ↗ · Checked 2026-11-08
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- The 1990s Biorhythmology and Rang-97 records were reanalyzed; they are not new human recruits. The 2022–2024 physiology studies were separate.
- The conclusions do not provide numerical comparisons between the five preparations.
- The accessible account associates HIF-1α and TSPO measurements with stress physiology and discusses the nonpeptide DMAE derivative separately; a Pineamin-mediated biomarker mechanism is not established.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Dissertation catalog, Chapter 6.4 heading, methods summary and conclusions; 49-page author abstract cataloged but not retrieved; original comparison tables unavailable
Review depth: Reported methods, results and evidence limitations
Source access and review scope
Dissertation catalog, Chapter 6.4 heading, methods summary and conclusions; 49-page author abstract cataloged but not retrieved; original comparison tables unavailable
Recorded source-check date: 2026-11-08. This date does not imply a completed systematic review.
Source type: Dissertation
Citation and original source
Original source: A. E. Kim. Kim’s five-peptide stress comparison: Chapter 6.4 evidence audit Kirov Military Medical Academy doctoral dissertation, 359 pp.; 2024 bibliography, related catalog entry dated 2025 2024.
Molekul research summary: https://molekul.io/research/kim-five-peptides-2024. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entryRelated compound profiles
Cortexin
A tissue-derived preparation with Russian stroke, cognitive, pediatric and other clinical reports. Study designs vary; the independent stroke review is shown alongside favorable original reports. None validates the personal WHOOP diary.
Pineamin
A bovine pineal-gland polypeptide mixture investigated in menopausal symptoms, age-related melatonin physiology and reproductive research. It is distinct from Pinealon (EDR), synthetic Epitalon (AEDG), and the separately studied extract Epithalamin.
Prostatilen
A prostate-tissue-derived polypeptide preparation with historical urological clinical reports. It is distinct from the synthetic short peptide Prostamax.
Thymalin
Thymus-derived peptide mixture with historical Russian studies in autoimmune cytopenias and thyroiditis, alongside other treatments. It is distinct from synthetic Thymogen and Thymodepressin.
Thymogen
EW is discussed in the thymus-derived research program. Thymalin extract outcomes cannot be assigned to this defined peptide.