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[Proinflammatory cytokines - as a marker of the effectiveness of neuroprotection in children with perinatal nervous system damage].

Degtyareva VG, Drobyshev VA · 2025 · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova; 2025

Human comparative studyEnglish abstractSource linked
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Study findings

The report describes lower proinflammatory cytokine levels with Cortexin-containing care, particularly in the severe-injury subgroup.

Population and setting
146 infants with perinatal nervous-system injury, divided by severity and treatment
Evidence type
Human comparative study
Preparation
See the original report; formulation details require verification.
Source language
rus
Title source
Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

Study limitations

  • Cytokines are surrogate endpoints, not demonstrated long-term developmental benefit.
  • Treatment subgroup sizes and masking require full-text review.
  • Possible overlap with other pediatric reports has not been resolved.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Indexed record and abstract checked. Full methods and risk of bias have not been independently assessed.

Recorded source-check date: 2026-10-06. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.17116/jnevro202512506162

Citation and original source

Original source: Degtyareva VG, Drobyshev VA. [Proinflammatory cytokines - as a marker of the effectiveness of neuroprotection in children with perinatal nervous system damage]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova; 2025 2025.

Molekul research summary: https://molekul.io/research/recent-40577182. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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