Vascular polypeptides plus troxerutin in chronic venous disease: randomized trial
I. A. Suchkov, A. A. Kamaev, A. V. Chupin, S. V. Sapelkin, A. G. Burenin · 2026 · Journal of Venous Disorders / Flebologiya. 20(2):89–96
Reported findings and study design
190 participants in a double-blind randomized comparison; 95 per arm; troxerutin in both arms. Bovine-vessel polypeptide complex; brand not named in the checked abstract.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| VCSS, visit 4 | 2.33±1.31 versus 3.24±1.62; reported difference −0.92 points (95% CI −1.34 to −0.50), p<0.001. | |
| CIVIQ-20 improvement ≥5 points, visit 4 | 93.7% versus 75.8%; p=0.0006. | |
| Serious adverse events | None reported in the abstract; nonserious-event counts unavailable. |
Visit 4 was 30±3 days after treatment ended. The rounded displayed means subtract to −0.91; retain the authors’ −0.92 estimate. Confirm analysis methods and trade-name identity in the full paper.
Source for the extracted data ↗ · Checked 2026-11-06
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Full formulation, participant flow, prespecification and detailed harms require the paper.
- No serious adverse events reported does not mean no adverse events.
- This adjunctive venous trial is separate from the arterial trials and does not establish purified KED efficacy.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original publisher abstract; full article behind purchase access
Review depth: Complete original abstract checked
Source access and review scope
Original abstract; a manufacturer Slavinorm attribution is separate from the unnamed preparation in this abstract.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Original clinical journal publication
Citation and original source
Original source: I. A. Suchkov, A. A. Kamaev, A. V. Chupin, S. V. Sapelkin, A. G. Burenin. Vascular polypeptides plus troxerutin in chronic venous disease: randomized trial Journal of Venous Disorders / Flebologiya. 20(2):89–96 2026.
Molekul research summary: https://molekul.io/research/vessel-polypeptides-venous-rct-2026. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry