[Effects of introduction of short peptides before carotid artery occlusion on behaviour and caspase-3 activity in the brain of old rats].
Mendzheritskiĭ AM, Karantysh GV, Ivonina KO · 2011 · Advances in gerontology = Uspekhi gerontologii; 2011
Study findings
The report describes increased behavioral sleep and reduced exploratory, motivational and motor behavior after Pinealon pretreatment. It also reports a survival signal across peptide treatment and changes in caspase-3.
- Population and setting
- Old rats given peptides before carotid-artery occlusion
- Evidence type
- Animal / experimental
- Preparation
- See the original report; formulation details require verification.
- Source language
- rus
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Behavioral sleep in this injury model is not a measurement of human REM sleep.
- Reduced activity is not necessarily restorative sleep or improved cognition.
- Pretreatment before experimental ischemia is not evidence for treatment after a human stroke; numerical survival effects are not supplied in the abstract.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed publication and abstract checked; full methods and risk of bias have not been independently assessed.
Recorded source-check date: 2026-10-06. This date does not imply a completed systematic review.
Citation and original source
Original source: Mendzheritskiĭ AM, Karantysh GV, Ivonina KO. [Effects of introduction of short peptides before carotid artery occlusion on behaviour and caspase-3 activity in the brain of old rats]. Advances in gerontology = Uspekhi gerontologii; 2011 2011.
Molekul research summary: https://molekul.io/research/pinealon-21809624. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry