The effect of the amino acids and cardiogen on the development of myocard tissue culture from young and old rats
Chalisova NI, Lesniak VV, Balykina NA, Urt'eva SA, Urt'eva TA, Sukhonos IuA, Zhekalov AN · 2009 · Advances in gerontology = Uspekhi gerontologii 2009
Reported findings and study design
Cardiogen stimulated proliferation in heart-tissue cultures from young and old rats and reduced p53 expression. The tested concentration was 10⁻¹² M; the abstract gives no proliferation effect size.
Myocardial explants from rats aged 3 and 24 months.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Heart-explant response | Proliferation increased and p53 expression decreased; numerical effect size not supplied | |
| Test concentration | 10⁻¹² M |
Explanted rat tissue, not human cardiac recovery. Reduced p53 is an assay finding and cannot alone establish safety or tissue regeneration.
Source for the extracted data ↗ · Checked 2026-11-01
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Explanted rat tissue, not human cardiac recovery. Reduced p53 is an assay finding and cannot alone establish safety or tissue regeneration.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Indexed abstract checked
Source access and review scope
Original-publication metadata and indexed abstract checked in Europe PMC. No unavailable full-text figures inferred.
Recorded source-check date: 2026-11-01. This date does not imply a completed systematic review.
Source type: Journal publication
Citation and original source
Original source: Chalisova NI, Lesniak VV, Balykina NA, Urt'eva SA, Urt'eva TA, Sukhonos IuA, Zhekalov AN. The effect of the amino acids and cardiogen on the development of myocard tissue culture from young and old rats Advances in gerontology = Uspekhi gerontologii 2009 2009.
Molekul research summary: https://molekul.io/research/thin-20210190. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry