Cortexin: brain-derived polypeptide complex — RU2104702C1
В.Г. Морозов, В.Х. Хавинсон, О.В. Чайка, В.И. Семенова · 1998 · RU2104702C1 · patent family 20186299
Published 1998-02-20.
Reported patent results
Reported findings
The patent reports several clinical improvement proportions, but endpoint definitions, treatment allocation and comparator denominators are incomplete.
Cortexin-lineage patent clinical descriptions include 96 cranial-trauma patients, 50 epilepsy patients, 30 schoolchildren with other neurological complaints, and a separate 89-child cerebral-palsy series.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Cranial-trauma improvement | 76% reported positive clinical effect versus 40% with conventional treatment | Exact arm sizes and responder criteria are not sufficiently established |
| Cerebral-palsy series | Motor improvement 74%, mental-development improvement 65%, seizure-syndrome relief 41% | 89 children; overlapping outcomes, not mutually exclusive responder groups |
| Other neurological groups | Reduced seizures or headaches and changes in EEG/attention described | No aggregate numerical seizure-frequency comparison extracted |
Selected heterogeneous reports do not establish modern comparative efficacy, neural regeneration or pediatric treatment recommendations. The process patent and later publications may reuse clinical material.
Source for the extracted data ↗ · Checked 2026-11-06
Patent claims and provenance
Manufacturing. Claims describe a brain-tissue polypeptide preparation and its production, rather than a single defined synthetic peptide.
Historical preparation lineage does not authenticate every current product or establish disease-specific clinical benefit.
- Publication
- RU2104702C1 ↗ · 1998-02-20
- Earliest priority / filing
- 1996-10-16 / 1996-10-16
- Original applicant / assignee
- Общество с ограниченной ответственностью "Клиника Института биорегуляции и геронтологии"
- Indexed status
- Not shown; official status unverified · checked 2026-11-06
- Patent family
- 20186299 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Method of preparing the biologically active polypeptide complex normalizing brain functions from animal raw, pharmacological composition and its using
Inventors: В.Г. Морозов; В.Х. Хавинсон; О.В. Чайка; В.И. Семенова.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Historical preparation lineage does not authenticate every current product or establish disease-specific clinical benefit.
- Selected heterogeneous reports do not establish modern comparative efficacy, neural regeneration or pediatric treatment recommendations. The process patent and later publications may reuse clinical material.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-20186299. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: В.Г. Морозов, В.Х. Хавинсон, О.В. Чайка, В.И. Семенова. Cortexin: brain-derived polypeptide complex — RU2104702C1 RU2104702C1 · patent family 20186299 1998.
Molekul research summary: https://molekul.io/research/patent-ru2104702c1. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry