Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray
Anisimov SV, Khavinson VKh, Anisimov VN · 2004 · Neuro endocrinology letters 2004
Reported findings and study design
Cortagen changed 234 of 15,247 assayed cardiac transcripts (1.53%), matching 110 known genes. Maximum reported changes were 5.42-fold up and 2.86-fold down.
Female 6-month-old CBA mice given Cortagen injections for five days; cardiac gene-expression assay.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Transcripts with significant change | 234 / 15,247 (1.53%); 110 known genes | |
| Largest expression shifts | 5.42-fold up; 2.86-fold down | Paper reports signed values +5.42 and −2.86 |
The experiment measured mouse heart gene expression. Human peripheral-nerve claims in the introduction are background, not clinical results from this study.
Source for the extracted data ↗ · Checked 2026-11-01
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- The experiment measured mouse heart gene expression. Human peripheral-nerve claims in the introduction are background, not clinical results from this study.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Indexed abstract checked
Source access and review scope
Original-publication metadata and indexed abstract checked in Europe PMC. No unavailable full-text figures inferred.
Recorded source-check date: 2026-11-01. This date does not imply a completed systematic review.
Source type: Journal publication
Citation and original source
Original source: Anisimov SV, Khavinson VKh, Anisimov VN. Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray Neuro endocrinology letters 2004 2004.
Molekul research summary: https://molekul.io/research/thin-15159690. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry