Chemical Platform for the Preparation of Synthetic Orally Active Peptidomimetics with Hemoregulating Activity.

Deigin V, Ksenofontova O, Khrushchev A, Yatskin O, Goryacheva A, Ivanov V. · 2016 · ChemMedChem

Animal / experimentalEnglish abstractSource linked

This is Molekul’s research summary, not the original publication. Educational information only, not medical advice. Seek qualified healthcare help for medical conditions.

What does this source report?

Five cyclic analogues, numbered 3–7, were synthesized; three showed activity in experimental hematopoietic assays. Normal-marrow stimulation and post-irradiation recovery differ. Oral activity is not a pharmacokinetic measurement.

Population and setting: See original report; human, animal and laboratory components must be distinguished.
Evidence type: Animal / experimental
Preparation: Preparation-specific research; no equivalence inferred
Source language: eng
Title provenance: Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

Full methods, preparation identity and risk of bias require appraisal.
Related publications may share experiments; source count is not independent-study count.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Indexed metadata and abstract checked via Europe PMC. Original full methods not reviewed.

Recorded source-check date: 2026-10-02. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1002/cmdc.201600157

Cite and trace this record

Original source: Deigin V, Ksenofontova O, Khrushchev A, Yatskin O, Goryacheva A, Ivanov V.. Chemical Platform for the Preparation of Synthetic Orally Active Peptidomimetics with Hemoregulating Activity. ChemMedChem 2016.

Molekul research summary: https://molekul.io/research/gaps-27457274. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

Thymogen

EW is discussed in the thymus-derived research program. Thymalin extract outcomes cannot be assigned to this defined peptide.

Stemokin / Neogen

Synthetic Ile–Glu–Trp tripeptide (IEW), studied in hematopoietic experiments and Russian clinical immune research. It is distinct from whole tissue extracts.

Editorial policy and evidence standards