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Follicular melatonin as a predictor of assisted reproduction outcomes in anovulatory infertility

A. S. Vasilyeva, M. I. Bazina, S. A. Syromyatnikova, A. T. Egorova, O. L. Lopatina, E. A. Pozhilenkova, A. N. Narkevich · 2022 · Russian Bulletin of Obstetrician-Gynecologist. 22(2):32–39.

Uncontrolled human reportFull text availableSource linked

This is Molekul’s research summary, not the original publication. Educational information only, not medical advice. Seek qualified healthcare help for medical conditions.

Study findings

Follicular melatonin correlated with mature-oocyte and high-quality-embryo measures. The low-reserve group, only partly exposed to Pineamin, had the highest mean follicular melatonin.

Population and setting: 150 women in three groups; every third participant in the low-reserve group received Pineamin
Evidence type: Uncontrolled human report
Preparation: See the original report; formulation details require verification.
Source language: Russian
Title source: Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

Study limitations

This is not a randomized 150-person Pineamin trial. Group-level findings cannot isolate the treated subgroup.
Ovarian reserve and infertility causes differed between groups; correlations do not establish treatment causation.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Publisher abstract and study description inspected.

Recorded source-check date: 2026-10-07. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.17116/rosakush20222202132

Citation and original source

Original source: A. S. Vasilyeva, M. I. Bazina, S. A. Syromyatnikova, A. T. Egorova, O. L. Lopatina, E. A. Pozhilenkova, A. N. Narkevich. Follicular melatonin as a predictor of assisted reproduction outcomes in anovulatory infertility Russian Bulletin of Obstetrician-Gynecologist. 22(2):32–39. 2022.

Molekul research summary: https://molekul.io/research/pineamin-follicular-2022. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

Pineamin

A bovine pineal-gland polypeptide mixture investigated in menopausal symptoms, age-related melatonin physiology and reproductive research. It is distinct from Pinealon (EDR), synthetic Epitalon (AEDG), and the separately studied extract Epithalamin.

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