Pinealon / EDR: post-injury neurological use — US8524674B2
Vladimir Khatskelevich Khavinson, Evgeny Iosifovich Grigoriev, Vladimir Victorovich Malinin, Galina Anatolievna Ryzhak · 2013 · US8524674B2 · patent family 38171593
Published 2013-09-03.
Reported patent results
Reported findings
The report describes better corrective-test performance and an EEG alpha-index change after EDR-containing treatment.
Pinealon/EDR patent report of 25 patients with remote cranial-trauma consequences; two main groups described with severity-dependent treatment, but exact arm sizes not established.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Corrective test: characters registered | 2,429.6 ± 105.3 after EDR-containing treatment versus 1,967.5 ± 122.4 after conventional care | Reported pre-treatment value 1,519.1 ± 141.7 · After the course · p<0.05 versus conventional care |
| Corrective test: mistakes | 6.4 ± 1.1 versus 9.7 ± 1.2 | Pre-treatment value 12.6 ± 1.3 · p<0.05 versus conventional care |
| EEG alpha index | 47.9 ± 3.1 after EDR versus 42.4 ± 2.8 conventional care; baseline 35.7 ± 4.6 | The baseline and EDR value also appear in the Cortagen patent; independence is unresolved |
Small incompletely specified groups, severity-dependent exposures and overlapping numerical patterns require verification. EEG and attention tasks do not demonstrate neural regeneration or an independent replicated clinical effect.
Source for the extracted data ↗ · Checked 2026-11-06
Patent claims and provenance
Use. The US grant claims use of Glu-Asp-Arg for specified functional outcomes after brain-cortex injury.
This is a use claim with a disease-specific scope, not proof of general cognitive enhancement; family publications are not separate replications.
- Publication
- US8524674B2 ↗ · 2013-09-03
- Earliest priority / filing
- 2006-05-30 / 2012-08-15
- Original applicant / assignee
- SIA Peptides OOO
- Indexed status
- Expired - Fee Related · checked 2026-11-06
- Patent family
- 38171593 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Method of improving the conditioned reflex habit, the muscle tonus, or the motion coordination of a patient after suffering trauma to the brain cortex
Inventors: Vladimir Khatskelevich Khavinson; Evgeny Iosifovich Grigoriev; Vladimir Victorovich Malinin; Galina Anatolievna Ryzhak.
US8524674B2 · US20090105157A1 · EP2024388B1 · KR101289220B1 · ATE445633T1 · DE602006009848D1 · DK2024388T3 · EA010157B1 · IL194346A · RU2301678C1 · UA91136C2 · WO2007139431A1
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- This is a use claim with a disease-specific scope, not proof of general cognitive enhancement; family publications are not separate replications.
- Small incompletely specified groups, severity-dependent exposures and overlapping numerical patterns require verification. EEG and attention tasks do not demonstrate neural regeneration or an independent replicated clinical effect.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-38171593. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: Vladimir Khatskelevich Khavinson, Evgeny Iosifovich Grigoriev, Vladimir Victorovich Malinin, Galina Anatolievna Ryzhak. Pinealon / EDR: post-injury neurological use — US8524674B2 US8524674B2 · patent family 38171593 2013.
Molekul research summary: https://molekul.io/research/patent-us8524674b2. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry