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Endonasal Cortexin for chronic fatigue syndrome: 2020 conference abstract

T. V. Konchugova; E. V. Nesterova · 2020 · Problems of Balneology, Physiotherapy, and Exercise Therapy, 97(6), supplement, pp. 56–57

Indexed 2026-11-12.

Human comparative studyRussian source · see review scopeSource linked

Reported findings and study design

Reported findings

The proceedings describe a three-group comparison of endonasal drug electrophoresis, electrical stimulation alone and sham. The abstract does not give the Cortexin dose or exact procedure schedule.

Dose, route and schedule

The proceedings describe a three-group comparison of endonasal drug electrophoresis, electrical stimulation alone and sham. The abstract does not give the Cortexin dose or exact procedure schedule.

Protocol source ↗ · Original Russian conference abstract, pp. 56–57

Results · Original Russian conference abstract, pp. 56–57
MeasureResultComparison, timing and statistics
EEG and cognitionAuthors reported increased alpha-wave amplitude, lower abnormal delta-wave amplitude and improved cognitive test performance. The abstract supplies no numerical effects.
Follow-upThe authors described persistence for one year in most treated patients, without an exact denominator.

The abstract gives no enrollment dates, group means, masking details or modern ME/CFS diagnostic criteria. The 2017 paper coauthored by Melnikova cites her 2010 dissertation and reports the same 50/25/25 allocation as the 2020 abstract. Their EEG and cognitive results use nearly identical wording. The reports likely reuse the same cohort and contribute a single 100-person comparison to the evidence summary. Participant-level confirmation is unavailable.

Source for these results ↗ · Reviewed 2026-11-12

For research and education. Consult a qualified clinician for medical advice.

Study limitations and source details

Study limitations

  • The abstract gives no enrollment dates, group means, masking details or modern ME/CFS diagnostic criteria. The 2017 paper coauthored by Melnikova cites her 2010 dissertation and reports the same 50/25/25 allocation as the 2020 abstract. Their EEG and cognitive results use nearly identical wording. The reports likely reuse the same cohort and contribute a single 100-person comparison to the evidence summary. Participant-level confirmation is unavailable.

Related publications may cover the same research program or participants.

Source access

The proceedings describe a three-group comparison of endonasal drug electrophoresis, electrical stimulation alone and sham. The abstract does not give the Cortexin dose or exact procedure schedule.

Source reviewed 2026-11-12.

Source type: Conference abstract

Open source ↗

Citation and original source

Original source: T. V. Konchugova; E. V. Nesterova. Endonasal Cortexin for chronic fatigue syndrome: 2020 conference abstract Problems of Balneology, Physiotherapy, and Exercise Therapy, 97(6), supplement, pp. 56–57 2020.

Molekul research summary: https://molekul.io/research/cortexin-electrophoresis-cfs-2020. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

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