Bronchogen: AEDL respiratory peptide — US7625870B2
Vladimir Khatskelevich Khavinson, Galina Anatolievna Ryzhak, Evgeny Iosifovich Grigoriev, Irina Yurievna Ryadnova · 2009 · US7625870B2 · patent family 34960198
Published 2009-12-01.
Reported patent results
Narrative findings; numerical extraction incomplete
The patent reports lower lung-injury changes and stimulation of explant growth, with selected blood-count changes during longer exposure.
Bronchogen/AEDL preclinical lung-injury, organotypic culture and longer-term animal observations; no human respiratory trial established here.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Lung-injury findings | Less interstitial fibrosis, atelectatic change and cellular infiltration described | Experimental animal comparison; no transcribed clinical lung-function effect |
| Organotypic lung growth | Explant growth significantly stimulated over the stated 1–10 ng/mL range | Laboratory tissue model; not human airway regeneration |
| Longer-term blood counts | Leukocyte increase reported at six months; most other morphology/chemistry indices not significantly changed | An observed biological change, not proof of universal absence of adverse effects |
These results concern AEDL, not EDG Chonluten. Animal pathology and culture growth cannot establish clinical respiratory efficacy or long-term human safety.
Source for the extracted data ↗ · Checked 2026-11-06
Patent claims and provenance
Molecule. Claim 1 explicitly identifies the tetrapeptide Ala-Glu-Asp-Leu, with respiratory-function composition and method claims.
This is AEDL, not the EDG tripeptide Chonluten. A respiratory label or a secondary review citation cannot resolve that sequence difference.
- Publication
- US7625870B2 ↗ · 2009-12-01
- Earliest priority / filing
- 2004-06-22 / 2004-12-07
- Original applicant / assignee
- Access Bioscience CJSC
- Indexed status
- Expired - Fee Related · checked 2026-11-06
- Patent family
- 34960198 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Peptide substance restoring respiratory organs function
Inventors: Vladimir Khatskelevich Khavinson; Galina Anatolievna Ryzhak; Evgeny Iosifovich Grigoriev; Irina Yurievna Ryadnova.
US7625870B2 · EP1758922B8 · ATE386046T1 · DE602004011842T2 · ES2302068T3 · RU2255757C1 · WO2006001729A1
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- This is AEDL, not the EDG tripeptide Chonluten. A respiratory label or a secondary review citation cannot resolve that sequence difference.
- These results concern AEDL, not EDG Chonluten. Animal pathology and culture growth cannot establish clinical respiratory efficacy or long-term human safety.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-34960198. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: Vladimir Khatskelevich Khavinson, Galina Anatolievna Ryzhak, Evgeny Iosifovich Grigoriev, Irina Yurievna Ryadnova. Bronchogen: AEDL respiratory peptide — US7625870B2 US7625870B2 · patent family 34960198 2009.
Molekul research summary: https://molekul.io/research/patent-us7625870b2. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry