Interaction of the synthetic immunomodulatory dipeptide bestim with murine macrophages and thymocytes

What does this source report?

Radiolabeled gamma-D-Glu-L-Trp bound mouse immune cells; unlabeled Thymogen competed for binding. This supports a shared binding interaction under assay conditions, not equivalent immunological outcomes in people.

Population and setting

Murine macrophages, thymocytes and isolated membranes

Evidence type

In vitro

Preparation

See the original report; formulation details require verification.

Source language

See source; English abstract or translated patent text where available

Title provenance

Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

• Cell-binding experiment, not a clinical trial.
• Preserve gamma linkage and D/L stereochemistry; generic database synonyms may be misleading.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Review depth: Selected text reviewed

Source access and review scope

Selected original-source text checked; full methodological review pending.

Recorded source-check date: 2026-10-05. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1134/S1068162008010044

Cite and trace this record

Original source: Author unconfirmed. Interaction of the synthetic immunomodulatory dipeptide bestim with murine macrophages and thymocytes Primary source linked above 2008.

Molekul research summary: https://molekul.io/research/rp-bestim-binding-2008. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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