Peptide bioregulators in surgical treatment of chronic periapical odontogenic infection in older adults
A. G. Slugina, D. V. Balin, A. A. Serikov, A. K. Iordanishvili · 2015 · Kubanskii Nauchnyi Meditsinskii Vestnik. 1(150):114–118
Reported findings and study design
A later research lecture reports 13.5% higher bone-regenerate density with perioperative Cartalax than with controls. The original paper’s outcome tables remain unavailable.
2015 dental-surgery comparison in 53 older adults: 28 Cartalax and 25 controls. Cohort, regimen and density statement are reproduced in N. S. Linkova’s 2025 lecture.
Dose, route and schedule
The later lecture reports oral Cartalax, 2 capsules twice daily for 30 days before surgery and 30 days afterward. Controls healed under a blood clot after surgery. Capsule strength is not provided in that passage. This is the reported study regimen.
Protocol source ↗ · 2025 lecture by N. S. Linkova explicitly citing the 2015 article; not the original methods section
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Bone-regenerate density | 13.5% higher than controls | Reported in the 2025 research lecture citing the 2015 clinical paper; not independently checked against original tables · 6, 9 and 12 months |
| Overall bone-structure restoration | Achieved in both groups, according to the lecture | The reported difference concerns speed and density, not healing versus no healing |
| Speed of reparative bone formation | 17% faster, as described in the lecture | A later-source claim; original definition and calculation have not been verified |
| Participants | 53: 28 Cartalax and 25 controls | Ages 61–83; 15 men and 38 women; later lecture |
| Reported perioperative course | 2 capsules twice daily for 30 days before and 30 days after surgery | Later lecture; capsule strength not specified |
The percentage describes a bone-density comparison, not the amount of knee cartilage restored. Allocation, confidence intervals and adverse-event rates need the original paper. The lecture is not an independent clinical trial.
Source for the extracted data ↗ · Checked 2026-11-01
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- The full 2015 article and outcome tables have not been recovered; numerical treatment effects and adverse-event rates are not available from the checked abstract.
- The later lecture supplies group counts and regimen; randomization and masking are not established.
- Postoperative jaw-bone healing is a different outcome from regeneration of knee articular cartilage.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Russian journal abstract; 2025 research lecture reproduction of methods
Review depth: 2025 research lecture reproducing the 2015 study; original indexed abstract supports study identity but the numerical outcome has not been verified against the original tables; full 2015 article not recovered
Source access and review scope
2025 research lecture reproducing the 2015 study; original indexed abstract supports study identity but the numerical outcome has not been verified against the original tables; full 2015 article not recovered
Recorded source-check date: 2026-11-01. This date does not imply a completed systematic review.
Source type: Published clinical study; indexed abstract with separately attributed lecture methods
Citation and original source
Original source: A. G. Slugina, D. V. Balin, A. A. Serikov, A. K. Iordanishvili. Peptide bioregulators in surgical treatment of chronic periapical odontogenic infection in older adults Kubanskii Nauchnyi Meditsinskii Vestnik. 1(150):114–118 2015.
Molekul research summary: https://molekul.io/research/cartalax-dental-surgery-2015. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry