Cortexin in a Russian chronic fatigue syndrome comparison
V. N. Tsigan · 2010 · Russian Medical Journal, issue 16, p. 1004
Indexed 2026-11-12.
Reported findings and study design
Reported findings
Both groups received a package of treatments. The Cortexin group also received 10 mg intramuscularly daily for 10 days, with repeat courses when needed. The authors used a symptom-list definition in which post-exertional discomfort lasting more than 24 hours was one optional criterion.
Dose, route and schedule
Both groups received a package of treatments. The Cortexin group also received 10 mg intramuscularly daily for 10 days, with repeat courses when needed. The authors used a symptom-list definition in which post-exertional discomfort lasting more than 24 hours was one optional criterion.
Protocol source ↗ · Original source
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Clinical ratings in the Cortexin arm | 43/56 (77%) rated good, 11/56 (20%) satisfactory and 2/56 (4%) unsatisfactory. The corresponding distribution for the 22 comparison patients was not supplied. | |
| Visual-motor performance | The proportion rated substantially impaired fell from 33.7% to 19%, and moderately impaired from 36.5% to 12%, in a before-and-after comparison. |
Allocation and masking are unclear. Clinical ratings in the Cortexin group do not estimate a controlled effect. The historical case definition did not require PEM.
Source for these results ↗ · Reviewed 2026-11-12
For research and education. Consult a qualified clinician for medical advice.
Study limitations and source details
Study limitations
- Allocation and masking are unclear. Clinical ratings in the Cortexin group do not estimate a controlled effect. The historical case definition did not require PEM.
Source access
Both groups received a package of treatments. The Cortexin group also received 10 mg intramuscularly daily for 10 days, with repeat courses when needed. The authors used a symptom-list definition in which post-exertional discomfort lasting more than 24 hours was one optional criterion.
Source reviewed 2026-11-12.
Citation and original source
Original source: V. N. Tsigan. Cortexin in a Russian chronic fatigue syndrome comparison Russian Medical Journal, issue 16, p. 1004 2010.
Molekul research summary: https://molekul.io/research/cortexin-tsigan-cfs-2010. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry