Role of Mono- and Divalent Ions in Peptide Glu-Asp-Arg-DNA Interaction.
Silanteva IA, Komolkin AV, Morozova EA, Vorontsov-Velyaminov PN, Kasyanenko NA · 2019 · The journal of physical chemistry. B; 2019 Mar
Study findings
EDR interacted with DNA in the tested systems; magnesium promoted the interaction. The authors described partial entry into the major groove and contacts with guanine atoms.
- Population and setting
- Purified DNA, spectroscopy, NMR and molecular-dynamics experiments
- Evidence type
- In vitro
- Preparation
- See the original report; formulation details require verification.
- Source language
- eng
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Biophysical interaction does not establish targeted gene regulation in the living human brain.
- This is mechanistic research, not clinical efficacy or safety evidence.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed publication and abstract checked; full methods and risk of bias have not been independently assessed.
Recorded source-check date: 2026-10-06. This date does not imply a completed systematic review.
Citation and original source
Original source: Silanteva IA, Komolkin AV, Morozova EA, Vorontsov-Velyaminov PN, Kasyanenko NA. Role of Mono- and Divalent Ions in Peptide Glu-Asp-Arg-DNA Interaction. The journal of physical chemistry. B; 2019 Mar 2019.
Molekul research summary: https://molekul.io/research/pinealon-30762356. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry