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Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats

Novoseletskaya AV, Kiseleva NM, Zimina IV, Bystrova OV, Belova OV, Inozemtsev AN, Arion VY, Sergienko VI · 2015 · Bulletin of experimental biology and medicine 2015

Animal / experimentalEnglish abstractSource linked

Reported findings and study design

Tactivin restored learning after thymectomy in young rats, whereas splenic polypeptides did not. The reported treatment was 0.5 mg/kg for one month.

Rats thymectomized at three weeks of age; active-avoidance learning assay.

Reported findings and study figures · Primary-publication indexed abstract
MeasureResultComparison, timing and statistics
Active-avoidance learningRestored with Tactivin; splenic polypeptides ineffective
Reported regimen0.5 mg/kg for 1 month after surgery

An animal thymectomy model; no effect size, group counts or human cognitive outcomes are supplied in the indexed abstract.

Source for the extracted data ↗ · Checked 2026-11-01

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • An animal thymectomy model; no effect size, group counts or human cognitive outcomes are supplied in the indexed abstract.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Review depth: Indexed abstract checked

Source access and review scope

Original-publication metadata and indexed abstract checked in Europe PMC. No unavailable full-text figures inferred.

Recorded source-check date: 2026-11-01. This date does not imply a completed systematic review.

Source type: Journal publication

Open original source or index record ↗

DOI: 10.1007/s10517-015-3030-6

Citation and original source

Original source: Novoseletskaya AV, Kiseleva NM, Zimina IV, Bystrova OV, Belova OV, Inozemtsev AN, Arion VY, Sergienko VI. Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats Bulletin of experimental biology and medicine 2015 2015.

Molekul research summary: https://molekul.io/research/thin-26459479. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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