The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19.
Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A · 2023 · International journal of molecular sciences; 2023
Study findings
Thymalin and isolated KE/EW dipeptides reduced measured IL-1β, IL-6 and TNF-α production in an LPS-stimulated cell model.
- Population and setting
- Human peripheral blood mononuclear cells from four donors, plus molecular modeling
- Evidence type
- In vitro
- Source language
- eng
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Four donors; repeated laboratory measurements are not additional participants.
- This is not a COVID-19 treatment trial. Docking predictions do not prove the proposed DNA-binding mechanism in people.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed primary-publication abstract checked; full methods not appraised.
Recorded source-check date: 2026-10-11. This date does not imply a completed systematic review.
Citation and original source
Original source: Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A. The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19. International journal of molecular sciences; 2023 2023.
Molekul research summary: https://molekul.io/research/oct11-37686182. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry