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Meteoadaptogenic properties of peptide drugs in healthy volunteers

P. D. Shabanov, V. P. Ganapolsky, P. V. Aleksandrov · 2007 · Eksp Klin Farmakol. 70(6):41–47

Clinical trial / comparisonFull text availableSource linked
This is Molekul’s research summary, not the original publication. Educational information only, not medical advice. Seek qualified healthcare help for medical conditions.

What does this source report?

Cold, heat and simulated altitude experiments compared four preparations, placebo and historical no-drug measurements. Effects varied by compound and endpoint.

Population and setting
127 healthy men aged 20–24 across a three-day environmental programme; active groups reported as 10–20, placebo 8–10 per stage
Evidence type
Clinical trial / comparison
Preparation
See the original report; formulation details require verification.
Source language
See original publication
Title provenance
Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

  • Random allocation and blinding not established; historical controls and baseline differences limit attribution.
  • Exact arm-by-environment denominators remain unresolved; 127 is the programme total, not Noopept enrollment.
  • Experimental intranasal peptide preparations are not equivalent to marketed oral products.
  • No validated protection from heat illness, operational accidents or long-term harm.
  • Possible overlap with the Academy report; do not count as independent replication.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Document format: Original journal PDF

Review depth: Methods and selected tables; encoding limits

Related-report group: meteoadaptation-2007-overlap-unresolved. Reports in this group are not assumed to be independent trials.

Source access and review scope

Publisher PDF methods and selected tables checked. Cyrillic text encoding limits numerical transcription; full table-level verification remains incomplete.

Recorded source-check date: 2026-10-02. This date does not imply a completed systematic review.

Open original source or index record ↗

Cite and trace this record

Original source: P. D. Shabanov, V. P. Ganapolsky, P. V. Aleksandrov. Meteoadaptogenic properties of peptide drugs in healthy volunteers Eksp Klin Farmakol. 70(6):41–47 2007.

Molekul research summary: https://molekul.io/research/noopept-meteo-2007. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

Noopept

A defined synthetic dipeptide derivative connecting nootropic research with experimental environmental adaptation. Human chamber studies, clinical EEG reports and preclinical mechanisms address different questions; none establishes safe hazardous-work use.

Cortexin

A tissue-derived preparation with Russian stroke, cognitive, pediatric and other clinical reports. Study designs vary; the independent stroke review is shown alongside favorable original reports. None validates the personal WHOOP diary.

Dilept

An experimental neurotensin-related peptidomimetic (GZR-123), included in the 2007 environmental-chamber comparison.

Vinpotropil

A fixed piracetam–vinpocetine preparation used as a nonpeptide comparator in the 2007 environmental-chamber study.

Editorial policy and evidence standards