Therapeutic equivalence of intravenous and intramuscular dosage forms of Cortexin in ischemic strokes
Fedin AI, Khairova EN, Artyukov OP, Timchenko LV, Bazhenova OA, Gaiduk NV, Zykov MV · 2025 · Zh Nevrol Psikhiatr Im S S Korsakova 125(12):60-67. PMID 41524350
What does this source report?
Compares routes of active Cortexin administration. Both groups received active drug; the placebo injections maintained masking.
- Population and setting
- 490 stroke patients: 246 IV-first, 244 IM; double-dummy active comparison
- Evidence type
- Randomized trial
- Preparation
- See the original report; formulation details require verification.
- Source language
- Russian
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- This is an active-route equivalence comparison, not evidence of benefit versus no Cortexin.
- Noninferiority margin and full analysis require review; publication year is 2025 despite later indexing.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed abstract and citation checked via Europe PMC / PubMed; full methods and risk of bias not appraised.
Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.
Cite and trace this record
Original source: Fedin AI, Khairova EN, Artyukov OP, Timchenko LV, Bazhenova OA, Gaiduk NV, Zykov MV. Therapeutic equivalence of intravenous and intramuscular dosage forms of Cortexin in ischemic strokes Zh Nevrol Psikhiatr Im S S Korsakova 125(12):60-67. PMID 41524350 2025.
Molekul research summary: https://molekul.io/research/bio-41524350. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry