Cortexin and other adjuncts in military combined-injury rehabilitation
I. Yu. Khabarov · 2008 · Kirov Military Medical Academy candidate dissertation author abstract
Indexed 2026-11-09.
Related evidence maps: Military & occupational ↗
Reported findings and study design
Reported work-capacity scores rose from 516.0 to 569.3 with Cortexin and from 524.1 to 613.2 with Vinpotropil. Standard care fell from 526.1 to 509.8.
Author-described double-blind randomized adjunctive study. Outcomes at days 7 and 14 included asthenia, anxiety, memory and tapping-based performance. Control included B-vitamin injections.
Dose, route and schedule
Cortexin 10 mg intramuscularly once daily, Mexidol 100 mg intramuscularly once daily, or Vinpotropil one oral capsule three times daily as separate adjuncts. Standard-care comparator included B1 and B6 injections.
Protocol source ↗ · Author’s abstract transcription. Full dissertation and underlying records unavailable.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Cortexin · work-capacity score | 516.0±21.4 → 569.3±5.2 | Day 1 to day 14. Standard care 526.1±10.2 → 509.8±12.2. · Reported p<0.05 versus standard care |
| Vinpotropil · work-capacity score | 524.1±23.7 → 613.2±19.5 | Day 1 to day 14. Separate treatment arm. · Reported p<0.05 versus standard care |
| Cortexin · clinician-rated anxiety | 13.4±2.1 → 4.5±0.6 | Day 14. All arms showed some improvement. |
| Attrition | 16 early discharges; zero attributed to adverse effects | The abstract does not provide a comprehensive adverse-event table. |
This is short-term treatment research in hospitalized patients after trauma. The 60 analyzed are included within the 76 selected.
Source for the extracted data ↗ · Checked 2026-11-09
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Blinding implementation across different routes is unclear. Complete arm flow, attrition by arm and outcome units need the full dissertation.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Author’s abstract transcription. Full dissertation and underlying records unavailable.
Review depth: Reported methods, results and evidence limitations
Related-report group: khabarov-combined-injury-2008. Reports in this group are not assumed to be independent trials.
Source access and review scope
Author’s abstract transcription. Full dissertation and underlying records unavailable.
Recorded source-check date: 2026-11-09. This date does not imply a completed systematic review.
Source type: Kirov Military Medical Academy candidate dissertation author abstract
Citation and original source
Original source: I. Yu. Khabarov. Cortexin and other adjuncts in military combined-injury rehabilitation Kirov Military Medical Academy candidate dissertation author abstract 2008.
Molekul research summary: https://molekul.io/research/khabarov-combined-injury-2008. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entryRelated compound profiles
Cortexin
A tissue-derived preparation with Russian stroke, cognitive, pediatric and other clinical reports. Study designs vary; the independent stroke review is shown alongside favorable original reports. None validates the personal WHOOP diary.
Mexidol
A nonpeptide succinate preparation tested as a separate adjunct in Khabarov’s military trauma rehabilitation comparison.
Vinpotropil
A fixed piracetam–vinpocetine preparation used as a nonpeptide comparator in the 2007 environmental-chamber study.