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Mechanism of Biological Activity of Short Peptides: Cell Penetration and Epigenetic Regulation of Gene Expression

V. Kh. Khavinson, A. Yu. Solovyev, S. I. Tarnovskaya, N. S. Linkova · 2013 · Biology Bulletin Reviews 3(6):451–455

ReviewFull text availableSource linked
This is Molekul’s research summary, not the original publication. Educational information only, not medical advice. Seek qualified healthcare help for medical conditions.

What does this source report?

Mechanistic review with a table of 15 short peptides on page 453. Tissue labels in the research map are the authors’ proposed targets, not established clinical indications.

Population and setting
Review of earlier research
Evidence type
Review
Preparation
See the original report; formulation details require verification.
Source language
English
Title provenance
Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

  • Source-linked does not mean a completed risk-of-bias review.
  • A review is not an independent clinical replication; proposed mechanisms do not establish efficacy or safety.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Author-hosted English PDF and its peptide table checked. Each cited experiment remains a separate appraisal task.

Recorded source-check date: 2026-09-27. This date does not imply a completed systematic review.

Open original source or index record ↗

DOI: 10.1134/S2079086413060042

Cite and trace this record

Original source: V. Kh. Khavinson, A. Yu. Solovyev, S. I. Tarnovskaya, N. S. Linkova. Mechanism of Biological Activity of Short Peptides: Cell Penetration and Epigenetic Regulation of Gene Expression Biology Bulletin Reviews 3(6):451–455 2013.

Molekul research summary: https://molekul.io/research/short-peptides-2013. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

Thymogen

EW is discussed in the thymus-derived research program. Thymalin extract outcomes cannot be assigned to this defined peptide.

Vilon

A peptide research entry in the Khavinson evidence map. Direct studies, related extract findings, institute reports and unresolved claims are distinguished below.

Normophthal

Listed in the 2013 short-peptide review under the authors’ proposed retina target. This historical label is not an established indication. Underlying studies need individual review.

Cartalax

AED research is distinct from PCC. The linked animal and cell papers, and a small patent-reported human comparison, do not establish cartilage regeneration.

Pinealon

A peptide research entry in the Khavinson evidence map. Direct studies, related extract findings, institute reports and unresolved claims are distinguished below.

Chonluten

A peptide research entry in the Khavinson evidence map. Direct studies, related extract findings, institute reports and unresolved claims are distinguished below.

Vesugen

A peptide research entry in the Khavinson evidence map. Direct studies, related extract findings, institute reports and unresolved claims are distinguished below.

Epitalon

AEDG was detected in pineal complex, but the long-term Epithalamin patient studies concern the extract. Synthetic-peptide effects require their own evidence.

Prostamax

Listed in the 2013 short-peptide review under the authors’ proposed prostate target. This historical label is not an established indication. Underlying studies need individual review.

Livagen

The liver literature discusses Ventvil extract and KEDA/Livagen separately. Experimental fibrosis and hepatitis findings do not establish human treatment benefit.

Cortagen

Listed in the 2013 short-peptide review under the authors’ proposed brain target. This historical label is not an established indication. Underlying studies need individual review.

Pancragen

A peptide research entry in the Khavinson evidence map. Direct studies, related extract findings, institute reports and unresolved claims are distinguished below.

Cardiogen

The AEDR rat-infarction finding traces to a patent cited by the cardiovascular review. The molecular link to heart complex remains review-reported here.

Testagen

Catalogue entry with identity and compound-specific evidence unresolved. No sequence or clinical outcome is asserted from commercial naming alone.

Bronchogen

Listed in the 2013 short-peptide review under the authors’ proposed bronchi target. This historical label is not an established indication. Underlying studies need individual review.

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