Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.

Study findings

Maternal Pinealon treatment was associated with better offspring spatial learning and greater resistance of isolated cerebellar neurons to oxidative stress.

Population and setting

Offspring of rats exposed to elevated maternal methionine during pregnancy

Evidence type

Animal / experimental

Preparation

See the original report; formulation details require verification.

Source language

eng

Title source

Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

Study limitations

• A prenatal hyperhomocysteinemia model does not establish benefit in healthy adults.
• This experiment does not establish safety or justify use during human pregnancy.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Indexed publication and abstract checked; full methods and risk of bias have not been independently assessed.

Recorded source-check date: 2026-10-06. This date does not imply a completed systematic review.

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Citation and original source

Original source: Arutjunyan A, Kozina L, Stvolinskiy S, Bulygina Y, Mashkina A, Khavinson V. Pinealon protects the rat offspring from prenatal hyperhomocysteinemia. International journal of clinical and experimental medicine; 2012 2012.

Molekul research summary: https://molekul.io/research/pinealon-22567179. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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