The immunomodulating effect of vilozen and splenin in the treatment of patients with acute and chronic toxic-allergic hepatitis
Frolov VM, Peresadin NA, Vysotskiĭ IIu, Tishchenko AN, Pinskiĭ LL · 1993 · Likars'ka sprava 1993
Reported findings and study design
Vilosen plus Splenin was reported to speed clinical and immune normalization when added to usual hepatitis treatment. Of 181 patients assessed, 60 are explicitly described as receiving the combination.
65 acute and 116 chronic toxic-allergic hepatitis patients examined; 20 acute and 40 chronic patients received add-on Vilosen plus Splenin.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Combination result | Faster clinical-index and immune-homeostasis normalization reported; no numerical effect supplied | |
| Explicitly treated subset | 20 acute + 40 chronic patients | |
| Treatment course | 10–15 days; Vilosen plus intramuscular Splenin and usual care |
No numerical between-group outcome or allocation method is supplied. Splenin and background therapy prevent isolating Vilosen. The abstract’s intranasal/sublingual dose wording is ambiguous.
Source for the extracted data ↗ · Checked 2026-11-01
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- No numerical between-group outcome or allocation method is supplied. Splenin and background therapy prevent isolating Vilosen. The abstract’s intranasal/sublingual dose wording is ambiguous.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Indexed abstract checked
Source access and review scope
Original-publication metadata and indexed abstract checked in Europe PMC. No unavailable full-text figures inferred.
Recorded source-check date: 2026-11-01. This date does not imply a completed systematic review.
Source type: Journal publication
Citation and original source
Original source: Frolov VM, Peresadin NA, Vysotskiĭ IIu, Tishchenko AN, Pinskiĭ LL. The immunomodulating effect of vilozen and splenin in the treatment of patients with acute and chronic toxic-allergic hepatitis Likars'ka sprava 1993 1993.
Molekul research summary: https://molekul.io/research/thin-8209504. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry