Pinealon during gestation: survival, learning and caspase-3
A. M. Mendzheritskii, G. V. Karantysh, V. A. Abramchuk, G. A. Ryzhak · 2012 · Neurochemical Journal. 2012;6(3):218–222. Russian original Neirokhimiya 29(3):229–234
Maternal exposure in animals · Pregnancy and offspring evidence review ↗
Reported findings and study design
Narrative findings; numerical extraction incomplete
The publisher abstract reports improved newborn survival and reduced learning disruption after maternal Pinealon, with effects varying by hypoxia timing. It gives no numerical treatment effect or group denominator.
Maternal treatment throughout pregnancy; prenatal hypoxia during different developmental windows; offspring behavior and brain caspase-3 measurements.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Survival and behavior | Qualitative improvement; prefetal/fetal hypoxia produced worse outcomes | Exact percentages and n unavailable in publisher abstract |
| Caspase-3 | Activity changed with developmental timing; a reduction alone does not prove reduced pathological cell death |
Publisher abstract only; numerical outcomes, allocation and litter handling require full text. The abstract prints Lys-Glu-Arg, conflicting with established Pinealon Glu-Asp-Arg. Preparation identity needs clarification. Russian Neirokhimiya and English Neurochemical Journal versions describe one paper, not two replications. The 2013 Abramchuk dissertation and conference reports may share this program.
Source for the extracted data ↗ · Checked 2026-11-08
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Publisher abstract only; numerical outcomes, allocation and litter handling require full text.
- The abstract prints Lys-Glu-Arg, conflicting with established Pinealon Glu-Asp-Arg. Preparation identity needs clarification.
- Russian Neirokhimiya and English Neurochemical Journal versions describe one paper, not two replications. The 2013 Abramchuk dissertation and conference reports may share this program.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Publication record and available text
Review depth: Original publisher abstract and translation metadata; full paper not recovered
Related-report group: rostov-prenatal-peptides-2012-2014. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original publisher abstract and translation metadata; full paper not recovered
Recorded source-check date: 2026-11-08. This date does not imply a completed systematic review.
Source type: Original journal publication
Citation and original source
Original source: A. M. Mendzheritskii, G. V. Karantysh, V. A. Abramchuk, G. A. Ryzhak. Pinealon during gestation: survival, learning and caspase-3 Neurochemical Journal. 2012;6(3):218–222. Russian original Neirokhimiya 29(3):229–234 2012.
Molekul research summary: https://molekul.io/research/pregnancy-pinealon-neurochemistry-2012. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry