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EDL: defined liver-regeneration peptide — RU2297239C1

Владимир Хацкелевич Хавинсон (RU), Владимир Хацкелевич Хавинсон, Евгений Иосифович Григорьев (RU), Евгений Иосифович Григорьев, Владимир Викторович Малинин (RU), Владимир Викторович Малинин, Галина Анатольевна Рыжак (RU), Галина Анатольевна Рыжак · 2007 · RU2297239C1 · patent family 38036774

Published 2007-04-20.

Patent / reported experimentsFull text availableSource linked

Reported patent results

Reported findings

The patent reports greater bilirubin reduction with EDL-containing care and a before/after ALT change.

EDL patent: 34 chronic-hepatitis patients, described as randomized into two groups; arm sizes and masking are not established.

Reported findings and study figures · Clinical comparison and Table 5; significance symbols read against the source footnotes.
MeasureResultComparison, timing and statistics
Bilirubin18.6 ± 1.4 after EDL versus 22.3 ± 1.1 conventional care; baseline 27.4 ± 1.7Table’s blanket unit label is unsuitable for all analytes; no corrected unit invented · p<0.05 versus conventional care
ALT41.7 ± 2.9 after EDL versus 46.2 ± 3.8 conventional care; baseline 54.5 ± 4.9Marked significant versus baseline, not clearly versus conventional care · p<0.05 versus baseline
AST and triglyceridesAST 39.5 ± 2.3 versus baseline 40.3 ± 3.2; triglycerides 2.4 ± 0.3 versus 2.3 ± 0.4Not marked significant; neutral chemistry retained

Missing arm sizes, severity-dependent exposures and biochemical endpoints prevent an established disease-modifying effect or proof of liver regeneration.

Source for the extracted data ↗ · Checked 2026-11-06

Patent claims and provenance

Molecule. The claims identify H-Glu-Asp-Leu-OH and related liver-regeneration compositions or uses.

The EDL sequence must not be confused with AEDL Bronchogen; commercial Ovagen equivalence has not been established here.

Publication
RU2297239C1 ↗ · 2007-04-20
Earliest priority / filing
2006-05-30 / 2006-05-30
Original applicant / assignee
Общество С Ограниченной Ответственностью "Сиа Пептайдс"
Indexed status
Not shown; official status unverified · checked 2026-11-06
Patent family
38036774 · family publications are related filings, not independent studies.
Original title, inventors and related publications

Peptide stimulating regeneration of liver tissue, pharmaceutical composition based on thereof and method for its using

Inventors: Владимир Хацкелевич Хавинсон (RU); Владимир Хацкелевич Хавинсон; Евгений Иосифович Григорьев (RU); Евгений Иосифович Григорьев; Владимир Викторович Малинин (RU); Владимир Викторович Малинин; Галина Анатольевна Рыжак (RU); Галина Анатольевна Рыжак.

RU2297239C1 · EA010156B1 · WO2007139430A1

Original patent PDF ↗

Patent collection and status interpretation →

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • The EDL sequence must not be confused with AEDL Bronchogen; commercial Ovagen equivalence has not been established here.
  • Missing arm sizes, severity-dependent exposures and biochemical endpoints prevent an established disease-modifying effect or proof of liver regeneration.
  • Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
  • Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Document format: Original patent text and indexed metadata

Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.

Related-report group: patent-family-38036774. Reports in this group are not assumed to be independent trials.

Source access and review scope

Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.

Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.

Source type: Patent publication

Open original source or index record ↗

Citation and original source

Original source: Владимир Хацкелевич Хавинсон (RU), Владимир Хацкелевич Хавинсон, Евгений Иосифович Григорьев (RU), Евгений Иосифович Григорьев, Владимир Викторович Малинин (RU), Владимир Викторович Малинин, Галина Анатольевна Рыжак (RU), Галина Анатольевна Рыжак. EDL: defined liver-regeneration peptide — RU2297239C1 RU2297239C1 · patent family 38036774 2007.

Molekul research summary: https://molekul.io/research/patent-ru2297239c1. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

Related compound profiles

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