Neuroprotective effects of peptides bioregulators in people of various age
R. S. Umnov, N. S. Linkova, V. Kh. Khavinson · 2013 · Adv Gerontol. 26(4):671–678. PMID 24738258
What does this source report?
A gateway review comparing polypeptide complexes (Cortexin and Cerebrolysin) with short peptides (Semax, Cortagen and Pinealon). It discusses older populations and cellular mechanisms; the abstract supplies no trial-quality assessment.
- Population and setting
- Review of earlier research
- Evidence type
- Review
- Preparation
- See the original report; formulation details require verification.
- Source language
- Russian
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Source-linked does not mean a completed risk-of-bias review.
- A review is not an independent clinical replication; proposed mechanisms do not establish efficacy or safety.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed English abstract checked; Russian full text not retrieved.
Recorded source-check date: 2026-09-27. This date does not imply a completed systematic review.
Cite and trace this record
Original source: R. S. Umnov, N. S. Linkova, V. Kh. Khavinson. Neuroprotective effects of peptides bioregulators in people of various age Adv Gerontol. 26(4):671–678. PMID 24738258 2013.
Molekul research summary: https://molekul.io/research/neuropeptides-2013. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entryRelated compound profiles
Cortexin
A tissue-derived preparation with Russian stroke, cognitive, pediatric and other clinical reports. Study designs vary; the independent stroke review is shown alongside favorable original reports. None validates the personal WHOOP diary.
Cerebrolysin
Porcine brain-derived peptide mixture studied in neurological disease, rehabilitation and laboratory models. Clinical results, composition analyses and unresolved archival leads are separated in this collection.
Semax
ACTH-fragment-derived peptide with clinical stroke and optic-nerve reports, healthy-volunteer imaging and preclinical neuroregulation research. Precursor, patent and dissertation sources remain separately labeled.
Cortagen
Listed in the 2013 short-peptide review under the authors’ proposed brain target. This historical label is not an established indication. Underlying studies need individual review.
Pinealon
A peptide research entry in the Khavinson evidence map. Direct studies, related extract findings, institute reports and unresolved claims are distinguished below.