Cheprasov’s Medilab peptide comparisons in aerospace stress
V. V. Cheprasov · 1997 · Kirov Military Medical Academy doctoral dissertation author abstract, Table 1 and methods
Indexed 2026-11-09.
Related evidence maps: Military & occupational ↗
Reported findings and study design
The three test series covered hypoxia, motion tolerance and 24 hours of work. The abstract reports favorable task results for selected peptides and gives a tiny separate postflight Thymogen comparison.
Hypobaric test: three arms of 10 at 5,000 m for 60 min. Motion: seven arms of 10 in a Coriolis test. Work: four arms of four at 50% of individually tolerated load. Postflight: four mission pairs, one participant per pair given Thymogen.
Dose, route and schedule
Hypoxia: intranasal Cortexin or Thymalin, 20 mg per course over two days, or placebo. Motion: single intranasal 5 mg Thymalin, Cortexin, Prostatilen or Epithalamin, or 50 µg Thymogen, with oral scopolamine 0.1 mg and placebo controls. Work: nasal Thymogen 100 µg or Cortexin 10 mg before work and after 6 and 12 h, or oral sydnocarb plus Bemitil, or saline. Postflight: intranasal Thymogen 100 µg/day for seven days.
Protocol source ↗ · Author’s abstract transcription. Full dissertation and underlying records unavailable.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Hypobaric comparison | Thymalin: 15–20% higher work measures; Cortexin: 10–15% improvement in selected operator measures | Abstract narrative; full arm-level estimates unavailable. |
| Coriolis motion tolerance | Cortexin +89%, Thymogen +73%, Epithalamin +68% | Reported tolerance-time improvement relative to control, ten per arm. |
| Sustained work | Author reported recovery of selected Thymogen-group measures to baseline by three hours | Four per arm. Cortexin and oral Bemitil plus sydnocarb were separate comparators. |
| Postflight respiratory infections | 1 of 4 in Thymogen arm versus 4 of 4 saline | Reported during the following year, a descriptive count from four pairs. |
| Program headcount | 328 stated; stage rows add to 338 | The 116 and 8 are subseries, with no additional headcount contributed to the historical tally. |
The aerospace findings concern separate stress and recovery tasks, with no reliable pooled treatment effect.
Source for the extracted data ↗ · Checked 2026-11-09
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Small comparisons, incomplete outcome reporting and unclear separation from related Medilab publications.
- The 47 modeling experts were outside the participant table.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Author’s abstract transcription. Full dissertation and underlying records unavailable.
Review depth: Reported methods, results and evidence limitations
Related-report group: cheprasov-medilab-1997. Reports in this group are not assumed to be independent trials.
Source access and review scope
Author’s abstract transcription. Full dissertation and underlying records unavailable.
Recorded source-check date: 2026-11-09. This date does not imply a completed systematic review.
Source type: Kirov Military Medical Academy doctoral dissertation author abstract, Table 1 and methods
Citation and original source
Original source: V. V. Cheprasov. Cheprasov’s Medilab peptide comparisons in aerospace stress Kirov Military Medical Academy doctoral dissertation author abstract, Table 1 and methods 1997.
Molekul research summary: https://molekul.io/research/cheprasov-peptide-performance-1997. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entryRelated compound profiles
Thymogen
EW is discussed in the thymus-derived research program. Thymalin extract outcomes cannot be assigned to this defined peptide.
Thymalin
Thymus-derived peptide mixture with historical Russian studies in autoimmune cytopenias and thyroiditis, alongside other treatments. It is distinct from synthetic Thymogen and Thymodepressin.
Cortexin
A tissue-derived preparation with Russian stroke, cognitive, pediatric and other clinical reports. Study designs vary; the independent stroke review is shown alongside favorable original reports. None validates the personal WHOOP diary.
Epithalamin
A pineal-gland tissue extract containing a mixture of peptides. Human aging and melatonin studies of this preparation must be distinguished from research on synthetic Epitalon (AEDG).
Prostatilen
A prostate-tissue-derived polypeptide preparation with historical urological clinical reports. It is distinct from the synthetic short peptide Prostamax.
Bemitil
A benzimidazole-derived actoprotector, also indexed as bemethyl and Metaprot. Research spans patient asthenia, occupational settings, neuromuscular and liver studies, metabolism and preclinical safety; these are research contexts, not established uses.