Modulating Effect of Peptide Therapy on the Morphofunctional State of Bronchial Epithelium in Rats with Obstructive Lung Pathology
Kuzubova NA, Lebedeva ES, Dvorakovskaya IV, Surkova EA, Platonova IS, Titova ON · 2015 · Bulletin of experimental biology and medicine 2015
Reported findings and study design
After one month of Bronchogen, rats showed less bronchial remodeling and neutrophilic inflammation, recovery of ciliated cells and increased secretory IgA. Numerical differences are not given in the abstract.
Rats exposed intermittently to nitrogen dioxide for 60 days to model obstructive lung disease.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Bronchial and immune findings | Remodeling and inflammatory changes improved; secretory IgA increased | |
| Model and treatment | 60-day NO₂ exposure; 1-month Bronchogen course |
A chemically induced rat model; related respiratory experiments may share the same research program. It does not establish prevention of human occupational lung injury.
Source for the extracted data ↗ · Checked 2026-11-01
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- A chemically induced rat model; related respiratory experiments may share the same research program. It does not establish prevention of human occupational lung injury.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Indexed abstract checked
Related-report group: bronchogen-no2-rat-program. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original-publication metadata and indexed abstract checked in Europe PMC. No unavailable full-text figures inferred.
Recorded source-check date: 2026-11-01. This date does not imply a completed systematic review.
Source type: Journal publication
Citation and original source
Original source: Kuzubova NA, Lebedeva ES, Dvorakovskaya IV, Surkova EA, Platonova IS, Titova ON. Modulating Effect of Peptide Therapy on the Morphofunctional State of Bronchial Epithelium in Rats with Obstructive Lung Pathology Bulletin of experimental biology and medicine 2015 2015.
Molekul research summary: https://molekul.io/research/thin-26468022. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry