Neurotropic Effects of Cortexin on Models of Mental and Physical Developmental Delay.
Kurkin DV, Bakulin DA, Morkovin EI, Petrov VI, Strygin AV, Smirnov AV, Shmidt MV, Gorbunova JV, Kolosov YA, Ivanova OV, Krysanov IS, Dzhavakhyan MA, Zaborovsky AV, Saparova VB, Makarenko IE, Drai RI, Lugovik IA, Verlov NA, Burdakov VS · 2025 · Biomedicines; 2025 Apr
Study findings
Cortexin improved selected behavioral and histological measures in models involving maternal alcohol exposure or neonatal hypoxia–ischemia.
- Population and setting
- Rat developmental-delay models; separate radiolabel-distribution experiments in mice
- Evidence type
- Animal / experimental
- Preparation
- See the original report; formulation details require verification.
- Source language
- eng
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- These are animal experiments, not a pediatric clinical trial.
- Distribution of radioiodine label does not prove transport of intact active peptides into the brain.
- The paper discloses Pharm-Holding employees among the authors; independent replication remains important.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed record and abstract checked. Full methods and risk of bias have not been independently assessed. Open full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC12024793/
Recorded source-check date: 2026-10-06. This date does not imply a completed systematic review.
Citation and original source
Original source: Kurkin DV, Bakulin DA, Morkovin EI, Petrov VI, Strygin AV, Smirnov AV, Shmidt MV, Gorbunova JV, Kolosov YA, Ivanova OV, Krysanov IS, Dzhavakhyan MA, Zaborovsky AV, Saparova VB, Makarenko IE, Drai RI, Lugovik IA, Verlov NA, Burdakov VS. Neurotropic Effects of Cortexin on Models of Mental and Physical Developmental Delay. Biomedicines; 2025 Apr 2025.
Molekul research summary: https://molekul.io/research/recent-40299434. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry