Research gaps.
Visible and specific.
A source-coverage check across 111 compound and family profiles. This is an editorial audit, not a systematic review or a clinical evidence rating.
What changed
- Card findings now show two selected results with limitations. Clinical reports, neutral results and relevant safety findings receive deliberate placement.
- 26 records were added: primary journal abstracts and separately labeled institute-report reproductions. Original experiments now supplement several previously review-only profiles.
- Six brochure reports received population and table checks. Signed originals, protocols, translation accuracy and independent replication remain unauthenticated.
- The NT-3 erratum was resolved as an author-name correction. Two Cerebrolysin reviews received full-text reporting checks; denominator and cohort issues remain open.
- Pirabel and B-300 original-report searches remain incomplete. No unsupported effect estimates or synergy claims were added.
Profile-by-profile priorities
Counts below describe linked publication records, including reports and overlapping publications. “Original-report records” excludes reviews, patents and citation-only leads but does not imply low risk of bias.
1 profile(s) have no linked study record; 5 have no eligible original-report findings; 51 have no linked human-intervention report.
Cortexin ↗
44 linked records · 37 original-report records · 33 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Semax ↗
11 linked records · 9 original-report records · 5 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Pinealon ↗
13 linked records · 8 original-report records · 2 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Epitalon ↗
12 linked records · 8 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Thymalin ↗
10 linked records · 7 original-report records · 3 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Vilon ↗
12 linked records · 10 original-report records · 2 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Vesugen ↗
11 linked records · 9 original-report records · 3 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Selank ↗
9 linked records · 8 original-report records · 4 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Bromantane ↗
34 linked records · 28 original-report records · 7 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Bemitil ↗
27 linked records · 23 original-report records · 13 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Piracetam ↗
19 linked records · 13 original-report records · 10 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Pirabel ↗
2 linked records · 2 original-report records · 2 human-report records
Recover the original reports cited in the 2019 monograph pp. 184–189 and the complete Kim dissertation. Reconcile shared volunteers and allocation; absence of a piracetam-only arm prevents a synergy claim.
Trekrezan ↗
6 linked records · 4 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Picamilon ↗
14 linked records · 14 original-report records · 5 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Etomerzol ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Bromitil ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Thymogen ↗
14 linked records · 8 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Normophthal ↗
1 linked records · 0 original-report records · 0 human-report records
Authenticate the original retinal/corneal reports, resolve eye-versus-patient denominators and confirm peptide linkage and formulation. A commercial reproduction is an acquisition lead.
Cartalax ↗
11 linked records · 8 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Chonluten ↗
3 linked records · 2 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Prostamax ↗
2 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Livagen ↗
4 linked records · 2 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Cortagen ↗
5 linked records · 3 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Pancragen ↗
7 linked records · 6 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Cardiogen ↗
4 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Testagen ↗
3 linked records · 2 original-report records · 0 human-report records
KEDG identity is supported by PMID 22117547. Human endocrine efficacy, long-term safety and equivalence to marketed formulations remain open.
Bronchogen ↗
4 linked records · 3 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Cerebrolysin ↗
17 linked records · 11 original-report records · 6 human-report records
Reconstruct the 2025 review’s CARS extraction and the 2026 review’s repeated follow-up denominators from original cohorts. Current numerical discrepancies remain unresolved.
KED ↗
7 linked records · 5 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
B-300 ↗
1 linked records · 1 original-report records · 1 human-report records
Retrieve the complete Elistratov and Ganapolsky dissertations and underlying experimental tables. Separate experimental formulations from later commercial proposals; review-level sample totals are not independent trials.
Noopept ↗
13 linked records · 7 original-report records · 2 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Phenotropil ↗
7 linked records · 7 original-report records · 4 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
PCC ↗
2 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Epithalamin ↗
6 linked records · 4 original-report records · 3 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Vasolin / Slavinorm ↗
2 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Ventvil ↗
2 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Prostatilen ↗
4 linked records · 3 original-report records · 2 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Retinalamin ↗
2 linked records · 1 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Ovagen ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Crystagen ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Actovegin ↗
3 linked records · 2 original-report records · 2 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Binavit ↗
5 linked records · 2 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
DSIP ↗
16 linked records · 14 original-report records · 4 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Haemalin ↗
5 linked records · 3 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Thymohaemin ↗
3 linked records · 3 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Thymohexin ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Vasonin ↗
2 linked records · 2 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Vilosen ↗
1 linked records · 0 original-report records · 0 human-report records
Recover the historical clinical papers behind thymus-extract references; distinguish nonprotein extract composition from synthetic peptides and patent case series.
Tactivin ↗
1 linked records · 1 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Thymodepressin ↗
10 linked records · 8 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Stemokin / Neogen ↗
6 linked records · 5 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
CP-88 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
AWE18 ↗
2 linked records · 1 original-report records · 0 human-report records
The original cyclic-peptide platform paper is now linked. Confirm the AWE18 development-code/compound-3 identity chain and recover toxicology reports; no human efficacy trial is established.
EDL ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Osteogenic growth peptide ↗
2 linked records · 2 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Gotratix ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Sigumir ↗
2 linked records · 2 original-report records · 2 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Taxorest ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Chelohart ↗
2 linked records · 2 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Suprefort ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Ventfort ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Endoluten ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Svetinorm ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Cerluten ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Vladonix ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Visoluten ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Pielotax ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Glandokort ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Bonomarlot ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Bonothyrk ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Stamakort ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Chitomur ↗
2 linked records · 2 original-report records · 2 human-report records
Retrieve both 2013 randomized reports in full: confirm sample sizes, concealment, prespecified endpoints, numerical effects and harms. Different populations are not interchangeable.
Testoluten ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Zhenoluten ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Tireogen ↗
1 linked records · 1 original-report records · 1 human-report records · 1 commercial reproductions
Authenticate the signed institute original and protocol; reconcile group denominators, background treatment and translation. Independent replication and current-product equivalence remain unverified.
Libidon ↗
0 linked records · 0 original-report records · 0 human-report records
Retrieve the original Libidon-specific clinical report and formulation description. Prostatilen and Prostamax studies cannot substitute for this preparation.
Dilept ↗
5 linked records · 4 original-report records · 2 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Vinpotropil ↗
1 linked records · 1 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Chlodantane ↗
8 linked records · 5 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Cyclontane ↗
3 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-918 ↗
6 linked records · 4 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-957 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-963 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-613 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Kemantane ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Camphane chlorobenzamide ↗
3 linked records · 3 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Adamantylaminoethyl chlorophenoxyacetate ↗
1 linked records · 0 original-report records · 0 human-report records
Recover the experimental results behind the chemistry record and verify exact structure. Synthesis alone does not establish pharmacological efficacy.
ADK-559 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-591 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-676 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-677 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-790 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-828 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
ADK-829 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Camphane aniline 4e ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Hypoxen / Olifen ↗
13 linked records · 9 original-report records · 3 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Dalargin ↗
7 linked records · 5 original-report records · 1 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
NGF mimetics: GK & GTS series ↗
7 linked records · 5 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
BDNF mimetics: GSB, GBK & GTS ↗
4 linked records · 3 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
NT-3 mimetics: GTS-301 & GTS-302 ↗
7 linked records · 5 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
GZS-411 ↗
1 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
CPG & GZK-111 ↗
8 linked records · 7 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Glyprolins & PGP hybrids ↗
2 linked records · 1 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Myelopid & MP-1–MP-6 ↗
6 linked records · 5 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
Sedatin & dermorphin analogues ↗
5 linked records · 4 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
NALE & peptide G ↗
3 linked records · 3 original-report records · 0 human-report records
Appraise original methods and replication; keep animal and cell findings separate from unestablished human benefit and safety.
GB-115 & CCK analogues ↗
5 linked records · 4 original-report records · 2 human-report records
Check full allocation, comparator, prespecified outcomes, effect estimates, harms and shared-cohort reporting before drawing a clinical conclusion.
Liberol / TRH research ↗
1 linked records · 0 original-report records · 0 human-report records
Retrieve the complete 2003 occupational dissertation, allocation tables and adverse-event data; a dissertation listing is not a verified treatment result.
Bestim ↗
3 linked records · 3 original-report records · 2 human-report records
Recover allocation, concurrent-treatment and adverse-event data for the psychiatric and ulcer reports; they do not isolate an independent Bestim effect.
Imunofan ↗
4 linked records · 4 original-report records · 2 human-report records
Appraise the 69-patient diabetic-foot trial in full and distinguish ulcer-cell markers from clinical healing. Preserve the separate animal hyperalgesia signal.
Gepon & ezrin-derived peptides ↗
4 linked records · 3 original-report records · 1 human-report records
Recover full clinical comparator and follow-up data. The 36-patient ulcerative-colitis response proportion is uncontrolled; mouse and fibroblast experiments provide mechanistic context only.