COMPOUND RECORD / BROMANTANE

BromantaneБромантан

PerformanceStress

Source linked

Research profile — evidence review incomplete. Topic tags are research navigation, not indications or recommendations. Source access does not establish effectiveness or safety.

01 / OVERVIEW

What is it?

A synthetic adamantane-derived compound studied in Russian fatigue and stress research. It belongs to the actoprotector literature and is not a peptide.

Identity / background source ↗

Research context

An actoprotector research entry linked to a small human comparison and an experimental neuropharmacology paper. The findings concern specific settings, not general performance or sleep benefits.

Working classification: Actoprotector
Research collection: Actoprotection & occupational pharmacology · editorial grouping
Institutional provenance: Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow
Last evidence review: Full evidence review pending; source-check scope appears with each publication below.

02 / EVIDENCE DIMENSIONS

What do we know?

Human research: —Small comparison
Study methods: —10 volunteers + animal work
Independent replication: —Not assessed
Source access: —English abstracts
Safety evidence: —Not assessed

These are independent review fields, not a rating. Missing evidence in this starter does not mean no research exists.

03 / SOURCE TRAIL

Linked sources

Explore the research map and unresolved leads ↗

2000Human comparative studyEnglish abstract

The neuro- and psychophysiological effects of bromantane

O. A. Viatleva, V. G. Barchukov, I. S. Morozov, Iu. A. Salenko, E. N. Zhirnov · Voen Med Zh. 321(8):61–65, 96

The placebo comparison reported EEG and tremor changes, but no change in subjective state or principal operator-performance measures in rested participants.

Population / setting: 10 healthy volunteers
What was checked: PubMed record and English abstract checked; full paper not reviewed.

Limitations & review scope

Very small sample and single administration.
Randomization and allocation details were not established from the abstract.
The proposed relevance to fatigued operators was not demonstrated by this rested-volunteer comparison.

Source checked 2026-09-27. This is a source-linked record, not a completed evidence review.

Read the source ↗

1999Animal / experimentalEnglish abstract

The mechanisms of the neurotropic action of bromantan

I. S. Morozov, G. S. Pukhova, N. A. Avdulov, S. A. Sergeeva, A. A. Spasov, I. N. Iezhitsa · Eksp Klin Farmakol. 62(1):11–14

Experimental work examined dopamine, serotonin, and noradrenergic responses. These are mechanistic observations, not evidence of human cognitive or sleep benefits.

Population / setting: Animal experiments and synaptosomal assays
What was checked: PubMed record and English abstract checked.

Limitations & review scope

Species, assays, and exposures differ from everyday human use.
A neurotransmitter-related signal does not establish a clinical mechanism or long-term safety.

Source checked 2026-09-27. This is a source-linked record, not a completed evidence review.

Read the source ↗

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