Personal observations and sleep diary
A dated history of stack observations and a maritime sleep diary from six-on/six-off work.
At sea: the 100-day recap & vessel diary ↗
What felt most useful, with six-hour watches, cargo work, heat, split sleep and the October return to sea alongside the observations.
WHOOP export analysis ↗
30 sleep-bearing cycles through October 10, daily main-sleep and nap totals, and source-linked context. Late-October posted readings remain separate.
Related research ↗
Published research is assessed separately from personal observations.
Reported sleep changes
@PepMariner described changes in WHOOP-estimated deep and REM sleep after adding Cortexin. Later posts also describe readings falling below the earlier trend. Both increases and decreases are included.
- Design
- Uncontrolled personal diary
- Measurement
- Self-reported WHOOP estimates
- “Restorative” here
- Deep + REM as reported in the posts
- Coverage
- Selected public posts, not all nights
| Post date | Total sleep | Deep | REM | Deep + REM | Share of block | Source |
|---|---|---|---|---|---|---|
| 2026-09-11 | 4h 13m | 1h 18m | 0h 45m | 2h 03m | 48.6%Calculated from posted minutes | Original post ↗ |
| 2026-09-12 | 4h 12m | 0h 49m | 1h 00m | 1h 49m | 43.3%Calculated from posted minutes | Original post ↗ |
| 2026-09-13 | 4h 40m | Not recorded | Not recorded | 2h 42m | 57.9%Calculated from posted minutes | Original post ↗ |
| 2026-09-15 | 3h 04m | 1h 20m | 0h 30m | 1h 50m | 59.8%Calculated from posted minutes | Original post ↗ |
| 2026-09-25 | Not recorded | Not recorded | Not recorded | Not recorded | 67%Reported in post | Original post ↗ |
| 2026-10-03 | Not recorded | Not recorded | Not recorded | Not recorded | 40%Reported in post | Original post ↗ |
| 2026-10-31 | Not recorded | Not recorded | Not recorded | Not recorded | 70%Reported in post | Original post ↗ |
A larger percentage can coexist with a shorter sleep block. Missing durations remain missing; selected posts are not a complete baseline or time series. A wearable estimate is not a clinical sleep-stage measurement.
Dated observations
42 dated entries · personal reports and prospective plans are labeled separately
How the stack began
Described starting with Pinealon and Vilon during six-on/six-off work, then reporting less reliance on coffee, better perceived sharpness and mood, and feeling less depleted after returning home. Later expanded to a multi-compound stack.
Retrospective self-report without a controlled comparison. Perceived recovery and symptom changes do not demonstrate tissue healing or increased life expectancy.
Read @PepMariner’s original post ↗A planned work-hitch experiment
Listed a planned stack for the next period at sea and said he would report back after three weeks.
A plan is not evidence that every component was used or that an outcome occurred.
Read @PepMariner’s original post ↗Early peptide preferences
Named Vilon and Pinealon as personal favorites in the stack, especially at work.
Preference only; the quoted animal-study discussion is not a human outcome.
Read @PepMariner’s original post ↗Rest and perceived need for coffee
After reporting about five hours of off-watch sleep, said he felt good and did not feel an overwhelming need for coffee.
Concurrent sleep and multiple compounds confound attribution. The report does not establish adequate sleep or an isolated Bromantane effect.
Read @PepMariner’s original post ↗About a week and a half into the work stack
Reported more agile cognition, feeling less tired and work feeling easier while using several compounds during six-on/six-off work. The original post explicitly calls the report anecdotal.
Multiple simultaneous compounds, changing workload and sleep prevent attribution to any component.
Read @PepMariner’s original post ↗Bromantane and Pinealon stood out early
Recalled Bromantane and Pinealon as the first two compounds with a noticeable subjective effect at sea, before Cerebrolysin and the broader stack.
Retrospective impression; research analogies in the post do not establish the cause of the experience.
Read @PepMariner’s original post ↗A competing attribution after adding Cerebrolysin
Reported that poor sleep caused by noise or docking felt less disruptive on the following watch than on previous trips, and tentatively attributed the change to the newest compound, Cerebrolysin.
A new component is a hypothesis, not an isolated effect. Feeling less impaired does not demonstrate preserved objective performance or adequate sleep.
Read @PepMariner’s original post ↗Considering different combinations by work context
Said he planned to try Bromantane plus Bemitil at work, and separately Bemitil plus Picamilon during a navigational watch.
Prospective intention; no result or safety conclusion was reported in this post.
Read @PepMariner’s original post ↗Which compounds felt most useful at work
Described Pinealon, Cortexin and Bromantane/Bemitil as the highest-value parts of his work stack.
Personal comparative impression, without standardized outcomes or isolated interventions.
Read @PepMariner’s original post ↗Earlier sleep-block observation
Posted total sleep, deep and REM estimates during the ongoing work schedule. Values below are transcribed from the public post.
Selected wearable estimate, not a complete daily sleep total, controlled baseline or clinical sleep test.
Read @PepMariner’s original post ↗An early repeat reading
Reported 4h 12m asleep, with 49m deep and 1h REM. The post described four successive restorative totals after adding Cortexin, without a controlled baseline.
Values transcribed from public post text, not a raw WHOOP export.
Read @PepMariner’s original post ↗Nootropil during a six-hour watch
Reported preferring the subjective effect of Nootropil to modafinil in his work setting, describing clarity without feeling excessively stimulated. Explicitly called the experience n=1.
Subjective preference is not proof of improved task accuracy, safe watchkeeping, or a favorable drug comparison.
Read @PepMariner’s original post ↗Interest in Bemitil plus Trekrezan
Expressed interest in trying the Bemitil–Trekrezan combination discussed in the research.
Not a documented trial or outcome.
Read @PepMariner’s original post ↗After the midnight watch
Reported 4h 40m asleep and 2h 42m of WHOOP-estimated deep plus REM sleep while working six-on/six-off.
The percentage describes this sleep block, not total daily recovery or adequate sleep.
Read @PepMariner’s original post ↗Fatigue remained part of the record
Responded to a WHOOP fatigue-related warning and compared the work situation to the Bromantane/Bemitil fatigue research.
The post does not provide a standardized fatigue result or prove the stack prevented fatigue.
Read @PepMariner’s original post ↗Earlier sleep-block observation
Posted total sleep, deep and REM estimates during the ongoing work schedule. Values below are transcribed from the public post.
Selected wearable estimate, not a complete daily sleep total, controlled baseline or clinical sleep test.
Read @PepMariner’s original post ↗Feeling better after a vessel change
Reported getting extra sleep during a vessel change and still feeling good with Bromantane plus Bemitil after a missed day of sleep.
Extra sleep is an important concurrent change. Feeling good does not establish unimpaired performance after sleep loss.
Read @PepMariner’s original post ↗Picamilon added to a broader stack
Reported a subtle positive mood and focus effect after adding Picamilon, and described Nootropil as helpful on high-effort days. Listed a broader stack and a planned later switch from Cortexin to Cerebrolysin.
Several concurrent agents and a planned change prevent isolation of a Picamilon or Nootropil effect.
Read @PepMariner’s original post ↗The pattern across naps and main sleep
Reported a recurring pattern around half of sleep classified as restorative across naps and morning sleep. This is the author’s series description, not a reconstructed complete dataset.
No complete denominator, baseline series, or raw measurements available in this record.
Read @PepMariner’s original post ↗What stood out after ten days of Cortexin
Described more mental bandwidth without a conventional stimulant feeling, better mood, vivid dreams and unexpectedly high WHOOP deep/REM readings. Pinealon had previously stood out most; Cortexin had become the stronger subjective experience. Cerebrolysin felt more like a recovery component.
This recap explains what “useful” meant to the author: perceived capacity during work and the quality of short sleep blocks. The post also identifies sleep deprivation and the concurrent stack as possible contributors.
Read @PepMariner’s original post ↗Another possible contributor
Reported restorative sleep around 40–50% and wondered whether Bemitil might also contribute.
The proposed attribution is a personal hypothesis. Concurrent compounds prevent isolation of an effect.
Read @PepMariner’s original post ↗A higher percentage during a nap
Reported 67% restorative sleep and noted that naps seemed to have a higher restorative percentage than longer sleep blocks.
Reported percentage only; total duration and stage minutes have not been transcribed.
Read @PepMariner’s original post ↗Higher reported REM
Described almost 60% restorative sleep and a high-heat, high-strain workday with multiple compounds mentioned.
Approximate wording is preserved; no exact percentage is inferred.
Read @PepMariner’s original post ↗A demanding cargo-work watch
During hot deck work involving hoses and stiff valves, reported a positive mood and feeling less tired than on previous occasions. The post explicitly acknowledged only two experiences with the combination.
Self-reported experience under uncontrolled conditions. No standardized workload, objective error rate or physiological protection outcome was established.
Read @PepMariner’s original post ↗Below the earlier trend
Reported the first night below the earlier 40–50% range and questioned whether the perceived residual effect was fading.
A later decline is included to avoid showing only favorable observations.
Read @PepMariner’s original post ↗Follow-up: deep and REM below trend
Reported deep and REM below the earlier trend, while still taking oral Pinealon and Epitalon. Wondered whether the perceived Cortexin effect was more acute than persistent.
Competing explanations include schedule, workload, other compounds, natural variation, and wearable classification.
Read @PepMariner’s original post ↗Workload, perceived sharpness, and strain
The post explicitly noted only two data points, questioned differing strain under apparently similar conditions, and proposed cumulative effects as a hypothesis. Its quoted prior update described better mood and perceived sharpness during hot deck work.
No blinded comparison, matched workload, objective error measurement, or isolated-compound effect is available. This does not establish heat or occupational protection.
Read @PepMariner’s original post ↗The roughly 100-day retrospective
Named Cortexin and Bemitil as the highest-value compounds so far. Described a favorable impression of Bemitil + Bromantane + Nootropil during work in heat, while saying that more data were needed. A possible winter trial of Bemitil with Phenotropil was a future idea.
“100 days” refers to cumulative time at sea/work, not 100 consecutive days on every compound. The ranking describes personal usefulness; no heat-protection measurements were reported. The winter combination was a plan, not an outcome.
Read @PepMariner’s original post ↗Harder to wake after a pre-watch nap
Reported 40% restorative sleep, but said getting up had become harder over the previous day or so. Wondered whether the perceived residual Cortexin effect was diminishing.
This less favorable observation belongs alongside the higher readings. The proposed explanation is the author’s interpretation, not confirmation of a compound wearing off.
Read @PepMariner’s original post ↗Two days of missed automatic sleep detection
Said WHOOP had failed to pick up sleep for two days, requiring manual entry, and reported a restorative-sleep reading around 50%.
Manual entry and missed detection matter when comparing posts with the export. This note does not identify a one-to-one match to a particular exported episode.
Read @PepMariner’s original post ↗Epitalon alone did not always feel better
Reported not liking Epitalon alone because sleep felt worse, while feeling more rested with Pinealon and Epitalon together before sleep. Said Pinealon had been a favorite until Cortexin.
The later positive Epitalon block readings do not erase this earlier mixed experience. It is a personal comparison across different conditions, not a test of whether the combination outperforms either component.
Read @PepMariner’s original post ↗Weather disrupted sleep before crew change
Reported another poor attempt at sleep during worsening weather, while still feeling reasonably well. Said Bemitil was the only compound taken that day and raised cumulative stack effects as a possible explanation.
Weather and interrupted sleep provide important context for the wearable record. A report of feeling decent after poor sleep is a subjective observation, not a measurement of task accuracy.
Read @PepMariner’s original post ↗Leaving the vessel after more than a month
Reported flying home, returning to a normal sleep schedule and intending to take a break from compounds for a few days.
This is the transition relevant to the October 9–10 WHOOP measurements. Travel and a different sleep opportunity changed alongside the planned compound break; the post does not verify subsequent abstinence.
Read @PepMariner’s original post ↗Four-hour sleep and a nap: a retrospective comparison
Compared his own work routine to split-sleep schedules, saying that his main sleep at work was closer to four hours.
This helps explain why the diary distinguishes a main block, naps and total recorded sleep. It is not a new WHOOP export or evidence of a particular day’s sleep duration.
Read @PepMariner’s original post ↗Heading back to work
Said he was on his way back to work and intended to try Chlodantane alongside the usual peptides, with a fuller account to follow after boarding.
A return-to-work post establishes a transition, not an exact boarding time, complete regimen or observed response.
Read @PepMariner’s original post ↗First B-300 experiment aboard
Explicitly called this day one of a B-300 experiment, while continuing other compounds. Planned to track endurance, mental fatigue, sleep quality and recovery through the hitch.
This is a reported start, not a completed B-300 result. Because the other compounds continued, subsequent changes cannot be assigned to B-300 alone.
Read @PepMariner’s original post ↗Why Picamilon remained in the work plan
Said he intended to use Picamilon in the same way as on the previous hitch. The quoted earlier account described a calmer subjective state while trying to remain vigilant, rather than adding another stimulant.
The earlier experience explains the intended role. This post does not establish that Picamilon was taken on each watch or improved objective vigilance.
Read @PepMariner’s original post ↗Several components changed together
Described a GHK-Cu, Cartalax and KPV blend, with BPC-157/TB-500 kept separately for possible use.
This records another concurrent change in the experiment. Mentioning a preparation or keeping a compound available does not establish daily administration or a response.
Read @PepMariner’s original post ↗First sleep block: more than 60% deep + REM reported
Reported more than 60% restorative sleep in the first block after pre-sleep Epitalon. Listed Bemitil/Trekrezan, Vilon and Vesugen during the day, and Chlodantane on the night watch. Suspected that Bemitil might also influence sleep.
The percentage is the author’s posted reading for one block. Its duration and stage minutes are not transcribed here, and no matching late-October raw export is available. The proposed Bemitil/Chlodantane mechanisms remain hypotheses.
Read @PepMariner’s original post ↗Second sleep block and a hot day on deck
Reported about 55% restorative sleep for the second block after intranasal Epitalon before bed. Said the day-watch plan was Nootropil + B-300.
Both the percentage and temperature are approximate self-reports. The post does not state the temperature unit. The day-watch stack is prospective wording, and the block percentage is not a whole-day sleep total.
Read @PepMariner’s original post ↗Lower perceived strain for similar work
After roughly 30 days of observations, described the median wearable “strain” number as trending down for work he considered similar. Tentatively attributed much of this to Bemitil, comparing the experience with earlier Bromantane-only use.
No numeric median, paired workload measures or late-October export accompany the text. This is a hypothesis about a trend, not a calculated effect. Cargo timing and the wider stack are part of the comparison.
Read @PepMariner’s original post ↗A reported 70% restorative sleep block
Reported a personal high of 70% restorative sleep, intranasal Epitalon before sleep, and B-300 + Nootropil for the day watch.
70% is the posted wearable percentage, not a recomputed export value. Without the block duration, it cannot be converted into deep/REM minutes or compared as a daily sleep total.
Read @PepMariner’s original post ↗Limitations of the diary
Cause and effect
There is no randomized withdrawal, blinding, stable comparator, or isolated intervention.
Confounding
Watch schedules, naps, workload, heat, other compounds, and normal night-to-night variation can change the observations.
Generalization
One person’s experience does not establish efficacy, safety, adequate sleep, or fitness for safety-critical work.