Ladasten in neurasthenia and somatogenic asthenia: safety and therapeutic efficacy
A. S. Avedisova, T. Yu. Kulikova, O. I. Mikhailova · 2009 · Mental Disorders in General Medicine. 2009(1):57–60
What does this source report?
Single-blind, stratified randomized comparison reported symptom improvement over 28 days. Mild restlessness during treatment and transient dizziness after withdrawal were reported.
- Population and setting
- 40 patients: 20 per diagnosis, randomized within diagnosis to active treatment or placebo (10 per cell)
- Evidence type
- Randomized trial
- Preparation
- See the original report; formulation details require verification.
- Source language
- See linked publication
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- Four small groups; multiple symptom outcomes.
- Seven-day post-treatment observation cannot establish long-term dependence or safety.
- Overlap with other 2009 Ladasten reports remains unresolved; do not sum cohorts.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Publisher HTML article
Review depth: Methods, results and harms narrative
Related-report group: ladasten-2009-overlap-unresolved. Reports in this group are not assumed to be independent trials.
Source access and review scope
Publisher methods, results and harms narrative checked; image tables not independently transcribed.
Recorded source-check date: 2026-10-02. This date does not imply a completed systematic review.
Cite and trace this record
Original source: A. S. Avedisova, T. Yu. Kulikova, O. I. Mikhailova. Ladasten in neurasthenia and somatogenic asthenia: safety and therapeutic efficacy Mental Disorders in General Medicine. 2009(1):57–60 2009.
Molekul research summary: https://molekul.io/research/bromantane-avedisova-2009. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry