Effect of ladasten on the content of cytokine markers of inflammation and behavior of mice with experimental depression-like syndrome.
Tallerova AV, Kovalenko LP, Durnev AD, Durnev AD, Seredenin SB · 2011 · Bulletin of experimental biology and medicine; 2011 Nov
Study findings
In an LPS-induced mouse model, Ladasten reduced elevated TNF-alpha and IL-6 and attenuated behavioral disturbances. This is distinct from a clinical depression trial.
- Population and setting
- Animal or animal-tissue experiments
- Evidence type
- Animal / experimental
- Preparation
- See the original report; formulation details require verification.
- Source language
- eng
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Original full text and detailed methods have not been reviewed.
- Experimental findings do not establish human efficacy, dosing or long-term safety.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed citation and English abstract checked.
Recorded source-check date: 2026-10-07. This date does not imply a completed systematic review.
Citation and original source
Original source: Tallerova AV, Kovalenko LP, Durnev AD, Durnev AD, Seredenin SB. Effect of ladasten on the content of cytokine markers of inflammation and behavior of mice with experimental depression-like syndrome. Bulletin of experimental biology and medicine; 2011 Nov 2011.
Molekul research summary: https://molekul.io/research/brom-extra-22803040. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry