Experimental rationale for the use of drugs to increase the resistance of the human body to the combined action of carbon monoxide and hyperthermia]
Sedov AV, Lukicheva TA, Surovtsev NA, Akin'shin AV, Nazarov LIu, Miroshnik SV · 1993 · Meditsina truda i promyshlennaia ekologiia (9-10):10-11. PMID 8087458
What does this source report?
Compared placebo, Bemitil, Bromantane and their combination. The abstract favors Bromantane-containing groups under the experimental exposure.
- Population and setting
- Volunteers exposed to a combined heat and gas model; enrollment not given
- Evidence type
- Human comparative study
- Preparation
- See the original report; formulation details require verification.
- Source language
- Russian
- Title provenance
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
What are the limitations?
- The title identifies carbon monoxide, while the English abstract says carbon dioxide: the original Russian methods are needed to resolve this inconsistency.
- Randomization, blinding and effect sizes are not established by the abstract.
- Not evidence that toxic or heat exposure is safe, or a substitute for exposure controls.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed citation and abstract checked through Europe PMC / PubMed. Original methods and risk of bias not fully appraised.
Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.
Cite and trace this record
Original source: Sedov AV, Lukicheva TA, Surovtsev NA, Akin'shin AV, Nazarov LIu, Miroshnik SV. Experimental rationale for the use of drugs to increase the resistance of the human body to the combined action of carbon monoxide and hyperthermia] Meditsina truda i promyshlennaia ekologiia (9-10):10-11. PMID 8087458 1993.
Molekul research summary: https://molekul.io/research/acto-8087458. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entryRelated compound profiles
Bemitil
A benzimidazole-derived actoprotector, also indexed as bemethyl and Metaprot. Research spans patient asthenia, occupational settings, neuromuscular and liver studies, metabolism and preclinical safety; these are research contexts, not established uses.
Bromantane
An adamantane-derived small molecule, also known as Ladasten. The expanded archive connects clinical asthenia studies, operator experiments and preclinical mechanisms, with model-specific limitations and safety findings.