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Ladasten induces the expression of genes regulating dopamine biosynthesis in various structures of rat brain]

Vakhitova IuV, Iamidanov RS, Seredinin SB · 2004 · Eksperimental'naia i klinicheskaia farmakologiia 67(4):7-11. PMID 15500036

Animal / experimentalEnglish abstractSource linked
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What does this source report?

Reports changes in tyrosine hydroxylase and DOPA-decarboxylase gene expression alongside dopamine and L-DOPA measurements.

Population and setting
Rat striatum and hypothalamus
Evidence type
Animal / experimental
Preparation
See the original report; formulation details require verification.
Source language
Russian
Title provenance
Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.

What are the limitations?

  • Rat gene-expression findings do not establish lasting dopamine enhancement in humans.
  • Brain-region and time-dependent results should not be reduced to a single mechanism.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Source access and review scope

Indexed citation and abstract checked through Europe PMC / PubMed. Original methods and risk of bias not fully appraised.

Recorded source-check date: 2026-09-29. This date does not imply a completed systematic review.

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Cite and trace this record

Original source: Vakhitova IuV, Iamidanov RS, Seredinin SB. Ladasten induces the expression of genes regulating dopamine biosynthesis in various structures of rat brain] Eksperimental'naia i klinicheskaia farmakologiia 67(4):7-11. PMID 15500036 2004.

Molekul research summary: https://molekul.io/research/acto-15500036. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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