The antidepressant properties of Ladasten: a pilot study
E. B. Dubnitskaya, D. F. Pushkarev · 2010 · Mental Disorders in General Medicine. 2010;(3):34–38
Published 2010-09-08.
Reported findings and study design
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| CGI-I response at eight weeks | 66.7% Ladasten versus 80% escitalopram; p>0.05 | |
| Treatment completion | All 30 participants completed eight weeks |
Open-label groups of 15. This does not establish equivalence, noninferiority or superiority; permitted co-treatment and incomplete adverse-event denominators remain relevant.
Source for the extracted data ↗ · Checked 2026-11-05
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Open-label, small active-comparator trial; random-number-table allocation is reported, but concealment is not established.
- A nonsignificant difference does not establish equivalence or noninferiority.
- Adjunctive hypnotics were permitted. The reported tolerability advantage needs complete event denominators and independent replication.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Publisher text reviewed; image tables not independently transcribed
Source access and review scope
Original publisher text checked for allocation, completion, CGI-I response and its nonsignificant comparison.
Recorded source-check date: 2026-11-05. This date does not imply a completed systematic review.
Source type: Original journal publication
Citation and original source
Original source: E. B. Dubnitskaya, D. F. Pushkarev. The antidepressant properties of Ladasten: a pilot study Mental Disorders in General Medicine. 2010;(3):34–38 2010.
Molekul research summary: https://molekul.io/research/recovery-bromantane-depression-2010. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry