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Semax, normobaric hypoxia and short reaction tests in athletes

R. V. Tambovtseva, D. I. Sechin · 2019 · Theory and Practice of Physical Culture, publisher article and Tables 1–2

Indexed 2026-11-09.

Human comparative studyFull text availableSource linked

Related evidence maps: Military & occupational research ↗

Reported findings and study design

Post-test flash reaction time was 0.25 s with Semax, 0.24 s with hypoxia and 0.32 s with saline. Baseline differences and overlap with related conference cohorts remain unresolved.

Pre/post response to sound, flash and choice stimuli and hand tapping. Hypoxia was a 30-minute, 10%-oxygen exposure.

Protocol information

Intranasal Semax 0.1% or saline. The English source prints 500 mg, whereas related conference methods print 500 µg. Exact delivered dose for this report requires the original Russian methods.

Protocol source ↗ · Original publisher English text and tables, cross-checked with the 2019 issue index. Dose unit requires confirmation.

Reported findings and study figures · Original publisher English text and tables, cross-checked with the 2019 issue index. Dose unit requires confirmation.
MeasureResultComparison, timing and statistics
Flash reaction timeSemax 0.34±0.11 → 0.25±0.04 sHypoxia 0.27±0.05 → 0.24±0.04 s; saline 0.31±0.12 → 0.32±0.11 s. Post-test p=0.01 for each active arm vs saline as printed.
Choice reaction timePost-test Semax 0.32±0.06 s; hypoxia 0.33±0.06 s; saline 0.42±0.10 sTables report unadjusted group means.
Late tapping intervalSemax 60.41 → 55.47 tapsDirection varies by interval. A faster visual response did not imply uniform tapping improvement.

Short psychophysiological endpoints and baseline imbalances limit inference about sport performance.

Source for the extracted data ↗ · Checked 2026-11-09

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • The overlapping authors and matching arm sizes with the 2018 proceedings warrant comparison of recruitment records. The third arm is described differently.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Document format: Original publisher English text and tables, cross-checked with the 2019 issue index. Dose unit requires confirmation.

Review depth: Reported methods, results and evidence limitations

Related-report group: tambovtseva-sechin-athlete-tests. Reports in this group are not assumed to be independent trials.

Source access and review scope

Original publisher English text and tables, cross-checked with the 2019 issue index. Dose unit requires confirmation.

Recorded source-check date: 2026-11-09. This date does not imply a completed systematic review.

Source type: Theory and Practice of Physical Culture, publisher article and Tables 1–2

Open original source or index record ↗

Citation and original source

Original source: R. V. Tambovtseva, D. I. Sechin. Semax, normobaric hypoxia and short reaction tests in athletes Theory and Practice of Physical Culture, publisher article and Tables 1–2 2019.

Molekul research summary: https://molekul.io/research/tambovtseva-semax-hypoxia-athletes. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

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