Actoprotective screening of aminoethanol–Krebs-cycle derivatives
V. Ts. Bolotova, E. B. Shustov, S. V. Okovityi · 2020 · Pharmacy Formulas. 2020;2(4):28–35
Reported findings and study design
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| FDES in the heavier-load dose-response comparison | The largest reported increase did not reach statistical significance against placebo. |
Candidate selection is not evidence of consistent benefit across conditions.
Source for the extracted data ↗ · Checked 2026-11-06
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Mouse performance findings do not establish human fatigue treatment.
- FDES is a distinct experimental compound; it is not interchangeable with DMAE or succinate supplements.
- Overlap with the 2019 monograph’s aminoethanol program requires checking.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Publisher HTML
Review depth: Methods and results narrative checked; PDF tables not visually appraised
Source access and review scope
Publisher full text, including the neutral result under the heavier-load condition.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Original animal research
Open original source or index record ↗
DOI: 10.17816/phf50230
Citation and original source
Original source: V. Ts. Bolotova, E. B. Shustov, S. V. Okovityi. Actoprotective screening of aminoethanol–Krebs-cycle derivatives Pharmacy Formulas. 2020;2(4):28–35 2020.
Molekul research summary: https://molekul.io/research/shustov-aminoethanol-2020. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entryRelated compound profiles
Bemitil
A benzimidazole-derived actoprotector, also indexed as bemethyl and Metaprot. Research spans patient asthenia, occupational settings, neuromuscular and liver studies, metabolism and preclinical safety; these are research contexts, not established uses.
Aminoethanol derivatives
A collection of chemically distinct aminoethanol candidates: the diethylaminoethanol-derived FDES and the dimethylaminoethanol-derived ADK-17 program. Animal cognition, neuroprotection, pharmacokinetics and safety reports are separated by preparation. These names do not identify one interchangeable compound.