Efficacy of Cerebrolysin Treatment as an Add-On Therapy to Mechanical Thrombectomy in Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion in Anterior Circulation: Results of a 3-Month Follow-up of a Prospective, Open Label, Single-Center Study.
Staszewski J, Dębiec A, Strilciuc S, Gniadek-Olejniczak K, Piusinska-Macoch R, Balo D, Harston G, Stępień A, Brzozowski K, Zięcina P, Narloch J, Wierzbicki M, Piasecki P · 2025 · Translational stroke research. 2025.
Study findings
Functional independence at 90 days was reported in 68% of the Cerebrolysin group versus 44% of historical controls. Mortality at 30 and 90 days did not differ significantly.
- Population and setting
- 50 prospectively treated thrombectomy patients and 50 matched historical controls
- Evidence type
- Human comparative study
- Source language
- eng
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Nonrandomized, single-center historical-control comparison; matching cannot remove unmeasured confounding.
- Selected patients had good collateral circulation and successful reperfusion.
- The 2026 twelve-month report (PMID 41739286) follows this cohort; it is not an independent trial.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Review depth: Full-text methods and results check
Related-report group: NCT04904341. Reports in this group are not assumed to be independent trials.
Source access and review scope
Repository full text checked for design, participants and reported outcomes; no independent reanalysis.
Recorded source-check date: 2026-10-08. This date does not imply a completed systematic review.
Citation and original source
Original source: Staszewski J, Dębiec A, Strilciuc S, Gniadek-Olejniczak K, Piusinska-Macoch R, Balo D, Harston G, Stępień A, Brzozowski K, Zięcina P, Narloch J, Wierzbicki M, Piasecki P. Efficacy of Cerebrolysin Treatment as an Add-On Therapy to Mechanical Thrombectomy in Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion in Anterior Circulation: Results of a 3-Month Follow-up of a Prospective, Open Label, Single-Center Study. Translational stroke research. 2025. 2025.
Molekul research summary: https://molekul.io/research/refresh-40325343. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry