Noopept: N-acylprolyl peptide derivatives — US5439930A
Sergei B. Seredenin, Tatiana A. Voronina, Tatiana A. Gudasheva, Rita U. Ostrovskaya, Grigori G. Rozantsev, Alexander P. Skoldinov, Sergei S. Trophimov, James A. Halikas, Taisija L. Garibova · 1995 · US5439930A · patent family 27128028
Published 1995-08-08.
Reported patent results
Reported findings
The disclosure reports anti-amnesic and withdrawal-related behavioral effects, plus reduced weight gain in one repeated-treatment experiment.
Noopept/Compound I patent program using rodent amnesia, behavior and repeated-treatment observations.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Memory-related behavior | Compound I reported to counter experimental memory disruption in passive-avoidance tests | Animal proxy; numerical table values not independently transcribed |
| Repeated-treatment weight gain | 12% versus 24% in controls, relative to starting body weight | A separate three-week rat observation; no human weight-loss inference · 3 weeks |
| Withdrawal-related behavior | Reduced anxiety-like/aggressive responses described after benzodiazepine withdrawal | Not a human dependence-treatment trial |
The molecular patent covers a wider derivative class. Results remain candidate- and model-specific, and the weight-gain observation is retained rather than presenting only favorable behavioral claims.
Source for the extracted data ↗ · Checked 2026-11-06
Patent claims and provenance
Molecule. The molecular family includes phenylacetylprolylglycine ethyl ester, the structure associated with Noopept.
A broad chemical class and patent examples do not substitute for clinical cognition or safety evidence.
- Publication
- US5439930A ↗ · 1995-08-08
- Earliest priority / filing
- 1992-04-14 / 1992-10-14
- Original applicant / assignee
- Russian-American Institute for New Drug Development
- Indexed status
- Expired - Lifetime · checked 2026-11-06
- Patent family
- 27128028 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Biologically active n-acylprolydipeptides having antiamnestic, antihypoxic and anorexigenic effects
Inventors: Sergei B. Seredenin; Tatiana A. Voronina; Tatiana A. Gudasheva; Rita U. Ostrovskaya; Grigori G. Rozantsev; Alexander P. Skoldinov; Sergei S. Trophimov; James A. Halikas; Taisija L. Garibova.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- A broad chemical class and patent examples do not substitute for clinical cognition or safety evidence.
- The molecular patent covers a wider derivative class. Results remain candidate- and model-specific, and the weight-gain observation is retained rather than presenting only favorable behavioral claims.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-27128028. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: Sergei B. Seredenin, Tatiana A. Voronina, Tatiana A. Gudasheva, Rita U. Ostrovskaya, Grigori G. Rozantsev, Alexander P. Skoldinov, Sergei S. Trophimov, James A. Halikas, Taisija L. Garibova. Noopept: N-acylprolyl peptide derivatives — US5439930A US5439930A · patent family 27128028 1995.
Molekul research summary: https://molekul.io/research/patent-us5439930a. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry