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GHK-Cu: historical wound-healing patent — US4760051A

Loren R. Pickart · 1988 · US4760051A · patent family 24788792

Published 1988-07-26.

Patent / reported experimentsFull text availableSource linked

Reported patent results

Reported findings

The patent reports smaller remaining wound size after copper-peptide treatment.

Historical GHK-Cu/GHL-Cu pig-wound experiments using contralateral controls; multiple wounds per animal.

Reported findings and study figures · Pig-wound results, day-21 pooled comparison and coverage-specific narrative.
MeasureResultComparison, timing and statistics
Remaining wound sizeReported 64.9% ±22.1 reduction versus contralateral controls in 14 wounds on 8 pigsThis is remaining-area reduction, not the proportion of wounds completely healed · Day 21 · p=0.0023, pooled wounds
Across animalsFaster healing described in all 10 pigs studiedThe day-21 subset was smaller; wounds within an animal are not independent observations

Small animal experiments, varied wound coverings and pooled wounds limit precision. This is not evidence of a 64.9% human healing rate or a new clinical trial.

Source for the extracted data ↗ · Checked 2026-11-06

Patent claims and provenance

Use. The granted disclosure concerns copper peptide complexes, including GHK-Cu, for wound-healing applications.

Historical patent examples are not an independent modern clinical trial; an expired index label is not a freedom-to-operate opinion.

Publication
US4760051A ↗ · 1988-07-26
Earliest priority / filing
1985-01-24 / 1985-01-24
Original applicant / assignee
Individual
Indexed status
Expired - Lifetime · checked 2026-11-06
Patent family
24788792 · family publications are related filings, not independent studies.
Original title, inventors and related publications

Use of GHL-Cu as a wound-healing and anti-inflammatory agent

Inventors: Loren R. Pickart.

US4760051A · EP0189182B1 · JPH0674208B2 · ATE107310T1 · CA1286988C · DE3689909T2

Original patent PDF ↗

Patent collection and status interpretation →

Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.

Methods, limitations & source review

Study limitations

  • Historical patent examples are not an independent modern clinical trial; an expired index label is not a freedom-to-operate opinion.
  • Small animal experiments, varied wound coverings and pooled wounds limit precision. This is not evidence of a 64.9% human healing rate or a new clinical trial.
  • Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
  • Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.

Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.

Document format: Original patent text and indexed metadata

Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.

Related-report group: patent-family-24788792. Reports in this group are not assumed to be independent trials.

Source access and review scope

Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.

Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.

Source type: Patent publication

Open original source or index record ↗

Citation and original source

Original source: Loren R. Pickart. GHK-Cu: historical wound-healing patent — US4760051A US4760051A · patent family 24788792 1988.

Molekul research summary: https://molekul.io/research/patent-us4760051a. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.

Bibliography entry

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