GHK-Cu: historical wound-healing patent — US4760051A
Loren R. Pickart · 1988 · US4760051A · patent family 24788792
Published 1988-07-26.
Reported patent results
Reported findings
The patent reports smaller remaining wound size after copper-peptide treatment.
Historical GHK-Cu/GHL-Cu pig-wound experiments using contralateral controls; multiple wounds per animal.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Remaining wound size | Reported 64.9% ±22.1 reduction versus contralateral controls in 14 wounds on 8 pigs | This is remaining-area reduction, not the proportion of wounds completely healed · Day 21 · p=0.0023, pooled wounds |
| Across animals | Faster healing described in all 10 pigs studied | The day-21 subset was smaller; wounds within an animal are not independent observations |
Small animal experiments, varied wound coverings and pooled wounds limit precision. This is not evidence of a 64.9% human healing rate or a new clinical trial.
Source for the extracted data ↗ · Checked 2026-11-06
Patent claims and provenance
Use. The granted disclosure concerns copper peptide complexes, including GHK-Cu, for wound-healing applications.
Historical patent examples are not an independent modern clinical trial; an expired index label is not a freedom-to-operate opinion.
- Publication
- US4760051A ↗ · 1988-07-26
- Earliest priority / filing
- 1985-01-24 / 1985-01-24
- Original applicant / assignee
- Individual
- Indexed status
- Expired - Lifetime · checked 2026-11-06
- Patent family
- 24788792 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Use of GHL-Cu as a wound-healing and anti-inflammatory agent
Inventors: Loren R. Pickart.
US4760051A · EP0189182B1 · JPH0674208B2 · ATE107310T1 · CA1286988C · DE3689909T2
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Historical patent examples are not an independent modern clinical trial; an expired index label is not a freedom-to-operate opinion.
- Small animal experiments, varied wound coverings and pooled wounds limit precision. This is not evidence of a 64.9% human healing rate or a new clinical trial.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-24788792. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: Loren R. Pickart. GHK-Cu: historical wound-healing patent — US4760051A US4760051A · patent family 24788792 1988.
Molekul research summary: https://molekul.io/research/patent-us4760051a. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry