RU2709503C1: Selank in acute cold-water hypothermia models — RU2709503C1
L. A. Andreeva, V. P. Vdovichenko, E. A. Nemersky, A. Yu. Petrovskaya, A. K. Petrovsky, N. A. Smirnov, V. N. Fedorov, T. B. Fedorova · 2019 · RU2709503C1 · patent family 69006996
Published 2019-12-18.
Related evidence maps: Military & occupational ↗
Reported patent results
Reported findings
Applicant claims use of Selank for resistance to acute cooling, with separate rat swimming and survival examples.
20 rats in free swimming and 36 in a separate 60-minute 9°C flotation-collar model. Intranasal Selank 200 µg/kg, timing varied by arm.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Free swimming · Example 1 | 23% longer active swimming than saline | 10 rats per arm at 9°C; reported p<0.05. |
| Post-exposure arm · Example 2 | 40% survived the subsequent observation period | Only 25% of saline controls survived the first hour and all died by day 2. Patent reports a 3.2-fold first-hour survival comparison. |
| Pre- and post-exposure schedule | No reported improvement in final survival | Distinct from the post-exposure-only arm. |
Animal patent experiments. Human treatment of hypothermia is outside the evidence.
Source for the extracted data ↗ · Checked 2026-11-09
Patent claims and provenance
Use. Applicant claims use of Selank for resistance to acute cooling, with separate rat swimming and survival examples.
Animal patent experiments. Human treatment of hypothermia is outside the evidence.
- Publication
- RU2709503C1 ↗ · 2019-12-18
- Earliest priority / filing
- 2019-05-23 / 2019-05-23
- Original applicant / assignee
- Not established from accessed metadata
- Indexed status
- Not shown; official status unverified · checked 2026-11-09
- Patent family
- 69006996 · family publications are related filings, not independent studies.
Original title, inventors and related publications
Применение пептида Thr-Lys-Pro-Arg-Pro-Gly-Pro (селанк) для повышения резистентности организма к острой гипотермии
Inventors: L. A. Andreeva; V. P. Vdovichenko; E. A. Nemersky; A. Yu. Petrovskaya; A. K. Petrovsky; N. A. Smirnov; V. N. Fedorov; T. B. Fedorova.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- Animal patent experiments. Human treatment of hypothermia is outside the evidence.
- Animal patent experiments. Human treatment of hypothermia is outside the evidence.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-69006996. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-09. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: L. A. Andreeva, V. P. Vdovichenko, E. A. Nemersky, A. Yu. Petrovskaya, A. K. Petrovsky, N. A. Smirnov, V. N. Fedorov, T. B. Fedorova. RU2709503C1: Selank in acute cold-water hypothermia models — RU2709503C1 RU2709503C1 · patent family 69006996 2019.
Molekul research summary: https://molekul.io/research/patent-ru2709503c1. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry