GHK-GP: anxiolytic-use claim — RU2705592C1
Игорь Иванович Бобынцев, Марина Евгеньевна Алферова, Анна Николаевна Тенькова, Андрей Евгеньевич Белых, Антон Олегович Ворвуль, Ирина Артуровна Телегина, Юлия Александровна Музалева, Людмила Александровна Андреева, Николай Федорович Мясоедов · 2019 · RU2705592C1 · patent family 68579458
Published 2019-11-11.
Reported patent results
Narrative findings; numerical extraction incomplete
GHK-GP showed test- and exposure-dependent anxiolytic-like behavior.
Rat elevated-plus-maze and Vogel conflict tests of GHK-GP versus saline; numerical group-size and table values are not transcribed.
| Measure | Result | Comparison, timing and statistics |
|---|---|---|
| Elevated-plus-maze behavior | Less time in closed arms and more open-arm exploration at selected tested exposures | Reported significant comparisons against saline · p<0.05 |
| Vogel conflict behavior | More punished drinking at the highest tested exposure | A different behavioral test and exposure; not a human anxiety endpoint |
The source narrative identifies significant directions, but exact table means and group sizes were not extracted. Animal proxies do not establish human anxiolytic efficacy.
Source for the extracted data ↗ · Checked 2026-11-06
Patent claims and provenance
Use. The claims identify glycyl-histidyl-lysyl-glycyl-proline, GHK-GP, for an anxiolytic use supported by animal testing.
GHK-GP is a specific extension of GHK; rodent behavioral findings do not establish human anxiety treatment.
- Publication
- RU2705592C1 ↗ · 2019-11-11
- Earliest priority / filing
- 2019-02-26 / 2019-02-26
- Original applicant / assignee
- Федеральное государственное бюджетное образовательное учреждение высшего образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации
- Indexed status
- Not shown; official status unverified · checked 2026-11-06
- Patent family
- 68579458 · family publications are related filings, not independent studies.
Original title, inventors and related publications
USE OF PEPTIDE Gly-His-Lus-Gly-Pro TO ACHIEVE ANXIOLYTIC EFFECT
Inventors: Игорь Иванович Бобынцев; Марина Евгеньевна Алферова; Анна Николаевна Тенькова; Андрей Евгеньевич Белых; Антон Олегович Ворвуль; Ирина Артуровна Телегина; Юлия Александровна Музалева; Людмила Александровна Андреева; Николай Федорович Мясоедов.
Molekul summary of the linked publication. Educational information, not medical advice. Seek qualified healthcare help for medical conditions.
Methods, limitations & source review
Study limitations
- GHK-GP is a specific extension of GHK; rodent behavioral findings do not establish human anxiety treatment.
- The source narrative identifies significant directions, but exact table means and group sizes were not extracted. Animal proxies do not establish human anxiolytic efficacy.
- Patents record claimed inventions and supporting disclosures. Publication or grant does not establish clinical efficacy, safety or marketing approval. Members of one patent family and related journal reports can describe the same experiments.
- Status labels are Google Patents index snapshots for the displayed publication or application; the record gives its source-check date. Official registers and every national family member have not been independently checked. These labels do not establish freedom to operate.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Document format: Original patent text and indexed metadata
Review depth: Claims, selected reported findings and limitations reviewed; supporting experiments not comprehensively appraised.
Related-report group: patent-family-68579458. Reports in this group are not assumed to be independent trials.
Source access and review scope
Original patent publication accessed through Google Patents. Claims, selected reported findings and source limitations checked. The results section identifies the examples, tables and any numerical extraction gaps. No complete experimental audit, prosecution review or legal claim construction was performed.
Recorded source-check date: 2026-11-06. This date does not imply a completed systematic review.
Source type: Patent publication
Citation and original source
Original source: Игорь Иванович Бобынцев, Марина Евгеньевна Алферова, Анна Николаевна Тенькова, Андрей Евгеньевич Белых, Антон Олегович Ворвуль, Ирина Артуровна Телегина, Юлия Александровна Музалева, Людмила Александровна Андреева, Николай Федорович Мясоедов. GHK-GP: anxiolytic-use claim — RU2705592C1 RU2705592C1 · patent family 68579458 2019.
Molekul research summary: https://molekul.io/research/patent-ru2705592c1. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry