Peptide Modulator of TRPV1 Channel Increases Long-Term Potentiation in the Hippocampus and Reduces Anxiety and Fear in Mice Under Acute Stress
Authors not yet confirmed · 2026 · Marine Drugs. 2026;24(2):59.
Study findings
APHC3 enhanced hippocampal long-term potentiation in mouse preparations and produced anxiolytic-like effects in acute-stress behavioral tests.
- Population and setting
- Mouse behavior and hippocampal preparations
- Evidence type
- Animal / experimental
- Source language
- English
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Mouse and brain-slice experiments, not human anxiety treatment evidence.
- Intranasal administration does not itself prove brain delivery; peptide levels in brain tissue were not directly quantified.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Repository primary abstract checked; full-text resource retrieved. Detailed tables not independently appraised.
Recorded source-check date: 2026-10-11. This date does not imply a completed systematic review.
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DOI: 10.3390/md24020059
Citation and original source
Original source: Author unconfirmed. Peptide Modulator of TRPV1 Channel Increases Long-Term Potentiation in the Hippocampus and Reduces Anxiety and Fear in Mice Under Acute Stress Marine Drugs. 2026;24(2):59. 2026.
Molekul research summary: https://molekul.io/research/oct11-41745462. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry