Exosomes Released by Cerebrolysin-Treated Cerebral Endothelial Cells Reverse Fibrin- or tPA-Impaired Endothelial Cell Permeability.
Teng H, Li C, Wang M, Zhang J, Zhang Y, Chopp M, Zhang ZG · 2026 · Cells; 2026 May
Study findings
Exosomes from Cerebrolysin-treated cells improved barrier-related measures after fibrin or tPA challenge, with changes in inflammatory and tight-junction proteins.
- Population and setting
- Cerebral endothelial-cell permeability assays
- Evidence type
- In vitro
- Preparation
- See the original report; formulation details require verification.
- Source language
- eng
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Exosome preparations are not interchangeable with administered Cerebrolysin.
- Cell experiments do not establish clinical stroke benefit.
- Full methods and risk of bias have not been independently assessed.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed record and available abstract checked; full text not reviewed.
Recorded source-check date: 2026-10-07. This date does not imply a completed systematic review.
Citation and original source
Original source: Teng H, Li C, Wang M, Zhang J, Zhang Y, Chopp M, Zhang ZG. Exosomes Released by Cerebrolysin-Treated Cerebral Endothelial Cells Reverse Fibrin- or tPA-Impaired Endothelial Cell Permeability. Cells; 2026 May 2026.
Molekul research summary: https://molekul.io/research/cbl-update-42193943. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry