Combined citicoline and Cerebrolysin for neuroprotection in traumatic brain injury: a retrospective cohort analysis.
Schlager P, Grgac I, Herzer G, Trimmel H · 2025 · Frontiers in neurology; 2025
Study findings
Adding Cerebrolysin to citicoline was not associated with a statistically significant difference in neurological function or mortality at six months.
- Population and setting
- 80 patients with severe traumatic brain injury
- Evidence type
- Human comparative study
- Preparation
- See the original report; formulation details require verification.
- Source language
- eng
- Title source
- Title as recorded in the linked source or index. A separate original-language title has not been transcribed unless shown above.
Study limitations
- Retrospective, single-center comparison with baseline severity differences.
- A favorable trend does not establish efficacy or combination synergy.
- Full methods and risk of bias have not been independently assessed.
Publication counts are not counts of independent trials. Reviews, translations and reports sharing participants may overlap. Findings apply to the studied preparation, population and endpoints.
Source access and review scope
Indexed record and available abstract checked; full text not reviewed.
Recorded source-check date: 2026-10-07. This date does not imply a completed systematic review.
Citation and original source
Original source: Schlager P, Grgac I, Herzer G, Trimmel H. Combined citicoline and Cerebrolysin for neuroprotection in traumatic brain injury: a retrospective cohort analysis. Frontiers in neurology; 2025 2025.
Molekul research summary: https://molekul.io/research/cbl-update-41409218. Cite the original publication for its findings and this page when referring to Molekul’s summary or evidence appraisal.
Bibliography entry